Evidence map›Paper›PMID 40444061›Full record

ArticleCase reports in gastroenterology

Gluten-Associated Neurological Disorders: A Cases Series.

Vismaya S Bachu, Farinaz Ghodrati, Brent L Fogel, Guy A Weiss

Abstract read
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vismaya S BachuDepartment of Internal Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Farinaz GhodratiCeliac Disease Program, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Brent L FogelDepartment of Neurology and Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Guy A WeissDepartment of Internal Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gluten-associated disorders, including celiac disease (CeD) and non-celiac gluten sensitivity (NCGS), can present with various extraintestinal neurologic manifestations, including sensory neuropathy, ataxia, headaches, and seizures. Case Presentations: In this case series, we present 3 interesting patients with gluten-associated neurological disorders (GAND) across a spectrum of gluten-associated disorders severity, from gluten sensitivity, to CeD, to refractory CeD, illustrating variable presentations and treatment approaches for this underdiagnosed population. Conclusion: For many patients with neurological presentations who initially lack gastrointestinal symptoms, diagnosis remains challenging. Once diagnosed, while a gluten-free diet has been the mainstay of treating GAND for many years, this approach may only prevent progression of disease without reversal of symptoms. Further studies are needed to help guide the development and standardization of treatments for this patient population.

Indexed as

Celiac diseaseGluten-associated disordersGluten-associated neurological disordersGluten-free dietNon-celiac gluten sensitivity

Identifiers

PMID40444061
PMCPMC12121981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.