Evidence map›Paper›PMID 40444013›Full record

ArticleOpen medicine (Warsaw, Poland)2025

CA199 and CEA expression levels, and minimally invasive postoperative prognosis analysis in esophageal squamous carcinoma patients.

Cheng Ji, Lingjia Ji, Fei Wang, Anping Zhang, Liang Shen

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A rare case of pulmonary sequestration with elevated CA19-9 levels.Annals of medicine and surgery (2012) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cheng JiDepartment of Thoracic and Cardiac Surgery, Nantong First People's Hospital, Nantong, Jiangsu, 226000, China.
Lingjia JiNursing Group, Affiliated Hospital of Nantong University, Nantong, Jiangsu, 226000, China.
Fei WangDepartment of Thoracic and Cardiac Surgery, Nantong First People's Hospital, Nantong, Jiangsu, 226000, China.
Anping ZhangDepartment of Thoracic and Cardiac Surgery, Nantong First People's Hospital, Nantong, Jiangsu, 226000, China.
Liang ShenDepartment of Thoracic and Cardiac Surgery, Nantong First People's Hospital, No. 666 Shengli Road, Chongchuan District, Nantong, Jiangsu, 226000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study explores the factors related to the expression levels of carbohydrate antigen 199 (CA199) and carcinoembryonic antigen (CEA) and their association with poor postoperative prognosis in patients with esophageal squamous cell carcinoma (ESCC) who underwent minimally invasive resection. Methods: Eighty patients with ESCC who underwent minimally invasive surgery were divided into two groups: 40 with poor prognosis (recurrence) and 40 with good prognosis (no recurrence). Additionally, 80 healthy subjects were selected as a control group. Serum CA199 and CEA levels were measured before surgery and 3 and 6 months postoperatively. Results: The serum CA199 and CEA levels in the experimental group were significantly higher than in the control group ( Conclusion: Poor prognosis in ESCC patients after minimally invasive resection may be influenced by factors such as lymph node metastasis, lesion length, and tumor location. Elevated CA199 and CEA levels postoperatively can serve as predictors of poor prognosis in patients with ESCC.

Indexed as

CA199CEAesophageal squamous carcinomaprognosis analysis

Identifiers

PMID40444013
PMCPMC12120403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.