Evidence map›Paper›PMID 40443964›Full record

ArticleJournal of aging science2024

The Peroxidation of Lipids, Cellular Senescence and Aging.

T Blake Monroe, Paul D Robbins, David A Bernlohr

Abstract read
In one paragraph

Article in Journal of aging science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Cellular Senescence Triggered by Food and Environmental Genotoxins.International journal of molecular sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T Blake MonroeDepartment of Biochemistry, Molecular Biology and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA.
Paul D RobbinsDepartment of Biochemistry, Molecular Biology and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA.
David A BernlohrDepartment of Biochemistry, Molecular Biology and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA.

Funding

Midwest Murine-Tissue Mapping Center (MM-TMC)U54AG079754 · NIA · UNIVERSITY OF MINNESOTA · PI GR Scott Budinger, Sundeep Khosla · 2022 to 2026
$11.5M
Inflammation, Lipid Metabolism and SenescenceR01AG069819 · NIA · UNIVERSITY OF MINNESOTA · PI CAMELL, CHRISTINA · 2020 to 2024
$1.9M
Lipid Metabolism, Mitochondrial Stress, and SenescenceF32AG086035 · NIA · UNIVERSITY OF MINNESOTA · PI MONROE, BLAKE · 2024 to 2025
$80k
NIA NIH HHS F32 AG086035NIA NIH HHS R01 AG069819NIA NIH HHS U54 AG079754
6 · The paper itself

Abstract

The inducers of cellular senescence as a determinant in organismal aging are complex and likely driven by a combination of hormonal and metabolic factors. Lipids have recently been implicated as inducers of cellular senescence

Indexed as

AgingLipid peroxidesOxidative stressSenescence

Identifiers

PMID40443964
PMCPMC12121948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.