Evidence map›Paper›PMID 40443915›Full record

ArticleTherapeutic advances in pulmonary and critical care medicine

A Dynamic Cause of Cardiogenic Shock Identified on Point-of-Care Ultrasound: A Case Report.

Akhilesh Gonuguntla, Thomas M Ruli, David N Maynard, Steven Fox

Abstract readCase Reports
In one paragraph

Article in Therapeutic advances in pulmonary and critical care medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

David N MaynardDepartment of Medicine, Tinsley Harrison Internal Medicine Residency, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID https://orcid.org/0009-0009-7174-4035
Steven FoxDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID https://orcid.org/0000-0003-1492-3255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dynamic left ventricular outflow tract obstruction (dLVOTO) is an important cause of cardiogenic shock to consider as its management differs from garden-variety cardiogenic shock from systolic dysfunction. It is best suited for serial evaluation by point-of-care ultrasound (POCUS) as its dynamic nature may cause it to be missed on routine echocardiograms. We present a case of a 95-year-old male who presented for constipation and went into cardiac arrest after manual disimpaction. After intubation and advanced cardiovascular life support with eventual return of spontaneous circulation, the patient developed cardiogenic shock. He developed persistent lactic acidosis, increasing ventilator requirements, and worsening renal function despite diuresis and escalating epinephrine and norepinephrine requirements. POCUS revealed left ventricular systolic dysfunction with apical hypokinesis and basal hyperkinesis suspicious for stress-induced cardiomyopathy. Moreover, systolic anterior motion of the mitral valve on M-mode ultrasound and a left ventricular outflow tract pressure gradient of 46 mm Hg on spectral Doppler were noted, consistent with dLVOTO. On recognition of dLVOTO, epinephrine and norepinephrine were weaned after adding vasopressin and phenylephrine. The patient's clinical status drastically improved thereafter and he was weaned off vasopressors and the ventilator within 48 hours. POCUS techniques that are often excluded from basic critical care ultrasound exams are required to identify the characteristic features of hemodynamically significant dLVOTO. These features are important to recognize in cardiogenic shock as inotropes and diuresis can lead to paradoxical worsening of the dLVOTO. Instead, these patients should be managed with pure vasopressors and measures to increase left ventricular preload (beta blockers and intravenous fluids).

Indexed as

Cardiogenic shockcase reportdiagnostic ultrasounddynamic LVOT obstructionpoint of care

Identifiers

PMID40443915
PMCPMC12120535

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