ArticleOxford medical case reports2025
Effective non-surgical management of spinal cord compression from extra-medullary hematopoiesis with radiotherapy in thalassemia intermedia: a case report.
Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal cord compression (SCC) secondary to extramedullary hematopoiesis (EMH) represents a rare but critical manifestation in patients with hematologic conditions, including β-thalassemia intermedia (β-TI). While there is no standard guideline due to the rarity of EMH-induced SCC, this case report documents successful management with radiotherapy while avoiding high-risk surgical intervention. The patient was a 17-year-old male with β-TI who developed debilitating SCC attributable to a paraspinal EMH mass. Due to concerns regarding surgical morbidity, a 26Gy 13-session course of radiation was administered alongside adjunctive blood transfusions, Hydroxyurea, and Glucocorticoids. Marked improvement and subsequent resolution of neurological deficits occurred rapidly following treatment, with sustained regression of the EMH mass over 18 months of follow-up. The case demonstrates that radiotherapy can be an effective primary treatment for EMH-induced SCC in β-TI, emphasizing its safety and efficacy when immediate and significant clinical response is required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.