Evidence map›Paper›PMID 40443826›Full record

ArticleCanadian respiratory journal2025

Effect of Cumulative Tobacco Exposure on Blood Eosinophil Level in Chronic Obstructive Pulmonary Disease.

İlknur Kaya, Dilek Karadoğan, Merve Yumrukuz Şenel, Tahsin Gökhan Telatar, Metin Akgün

Abstract readMulticenter Study
In one paragraph

Article in Canadian respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

İlknur KayaDepartment of Chest Diseases, School of Medicine, Kütahya Health Sciences University, Kütahya, Turkey.ORCID 0000-0002-0227-9215
Dilek KaradoğanDepartment of Chest Diseases, School of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey.ORCID 0000-0001-5321-3964
Merve Yumrukuz ŞenelDepartment of Chest Diseases, School of Medicine, Balıkesir University, Balıkesir, Turkey.ORCID 0000-0003-0205-5075
Tahsin Gökhan TelatarDepartment of Public Health, School of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey.ORCID 0000-0002-3261-3464
Metin AkgünDepartment of Chest Disease, School of Medicine, Ağrı İbrahim Çeçen University, Ağrı, Turkey.ORCID 0000-0003-3404-4274

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is a lung condition characterized by persistent airway obstruction and is associated with various phenotypes and endotypes. While eosinophilic inflammation is typically seen in asthma, it also occurs in COPD, with known increases in eosinophil counts during exacerbations. However, the impact of cumulative tobacco exposure on eosinophil counts is not well understood. This study aims to investigate this relationship. Data for this prospective study were collected from three centers, involving patients diagnosed with COPD. Patients' demographic data and eosinophil levels were documented. They were categorized according to GOLD Stages A, B, and E, and each group was analyzed relative to the amount of cigarette smoking. The study enrolled 227 COPD patients, predominantly male (92.5%) with an average age of 64.6 years. Of the study population, 39.8% (

Indexed as

Cigarette SmokingEosinophilsPulmonary Disease, Chronic ObstructiveSmokingAdultAgedAged, 80 and overFemaleHumansLeukocyte CountMaleMiddle AgedProspective StudiesYoung AdultCOPDeosinophiltobacco exposure

Identifiers

PMID40443826
PMCPMC12122158

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.