ReviewAmerican journal of lifestyle medicine2025
Effects of Sleep Deprivation on Physical and Mental Health Outcomes: An Umbrella Review.
Review in American journal of lifestyle medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of progressive muscle relaxation on sleep quality in adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2026Pooled it
- Silibinin Alleviates Cognitive Dysfunction, Biochemical Alterations, and Hippocampal Structural Changes Induced by 5 days of Sleep Deprivation with or Without a Subsequent 24-H Recovery in Rats.Molecular neurobiology · 2026Article
- Sleep and mental illness: an umbrella review protocol.BMJ open · 2026Article
- Leisure-Time Physical Activity, Sleep, and Self-Perception of Health During the COVID-19 Lockdown in Québec.Epidemiologia (Basel, Switzerland) · 2026Article
- Beverage-Derived Caffeine Intake, Sleep Duration, and Mental Health Among Korean Adults: A Cross-Sectional Analysis of KNHANES 2021-2024.Nutrients · 2026Article
- Sleep and Disorders of Gut-Brain Interaction.Gastroenterology & hepatology · 2026Article
- Association Between Depressive Symptoms and Self-Reported Ongoing Medication Use Among Pharmacy Students: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Sleep Duration and Mortality in Women: Effect of Aging and Menopause.Sleep medicine clinics · 2026Review
- Randomised Evaluation of Sleep in Cognitive Impairment Trial (REST)-Protocol for a Feasibility Study of a Digital Cognitive Behavioural Therapy for Insomnia Intervention.International journal of environmental research and public health · 2026Article
- Heterogeneity of depressive symptoms and associated factors in Korean adults: a latent class analysis using a national data survey.Journal of Korean biological nursing science · 2026Article
- Relationship of Emotional Functioning in 9-12-Year-Old Schoolchildren with Key Lifestyles: Sleep Quality and Daily Physical Activity.Children (Basel, Switzerland) · 2026Article
- Association between sleep duration and intrinsic capacity in older adults: evidence from a longitudinal cohort study and Bayesian network analyses.BMC geriatrics · 2026Article
- The prevalence of short sleep duration and sleep disturbances among working-age adults in Poland - a secondary analysis.Frontiers in public health · 2026Article
- Amplified psychological reactions to war predict increased sleep problems among holocaust descendants.Frontiers in psychiatry · 2026Article
- "The heat really troubles us": community perspectives on a cool roof intervention, Umlazi, KwaZulu-Natal, South Africa.Frontiers in climate · 2026Article
- Article
- Holistic approaches to trauma rehabilitation for forced migrants: assessing sleep as an associated factor for mental health, pain, and cardiovascular health.Journal of migration and health · 2026Article
- Sleep Quality in Shift-Working Nurses: Subjective and Objective Evaluation.International journal of environmental research and public health · 2025Observational
- Restless nights, demanding days: assessment of the prevalence and associated factors of poor sleep quality among medical students in Mogadishu, Somalia.BMC medical education · 2025Article
- Sleep Disorders and Associated Factors Among Medical Students in Saudi Arabia: A Systematic Review and Meta-Analysis.Cureus · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing prevalence of reduced habitual sleep duration presents a significant public health challenge, impacting cardiovascular health, metabolic function and mental well-being. This umbrella review analyses findings from systematic reviews and meta-analyses to comprehensively evaluate the consequences of sleep deprivation (SD) on health. The databases searched included PubMed, Scopus, and Web of Science. Inclusion criteria focused on adult populations with SD and systematic reviews/meta-analyses. Twenty-nine articles were included in the final synthesis, encompassing a variety of health outcomes. Key findings highlight a U-shaped relationship between sleep duration and all-cause mortality, with both short (<7 h) sleep durations associated with increased risks. SD was a significant risk factor for cardiovascular diseases such as hypertension, stroke and coronary heart disease. Alongside heightened risks of metabolic disorders, like obesity and type 2 diabetes. Moreover, SD contributed to elevated anxiety levels, impaired emotional regulation. As well as increased susceptibility to stress and depressive symptoms. This synthesis underscores the critical importance of maintaining recommended sleep duration (typically 7-9 h for adults) to mitigate these health risks effectively. The findings support the need for robust public health interventions aimed at promoting healthy sleep habits to reduce the burden of associated health conditions and enhance overall well-being.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.