ArticleCureus2025
Postoperative Serotonin Syndrome Triggered by Propofol in a Patient on Chronic Serotonergic Medications and Bupropion: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Serotonin syndrome is a potentially life-threatening condition that is commonly associated with the use of serotonergic agonistic medications, such as selective serotonin reuptake inhibitors (SSRI), serotonin-norepinephrine reuptake inhibitors (SNRI), and opioids. In contrast, propofol, a commonly used perioperative induction and intravenous sedation medication, is not frequently reported to cause serotonin syndrome. We present a rare case in a 34-year-old female who developed serotonin syndrome in the postoperative setting after the administration of propofol for induction and maintenance of anesthesia. The patient presented postoperatively with diaphoresis and non-fatigable ocular and extremity clonus, at which time she received benzodiazepines and cyproheptadine after discontinuing the offending agent. The patient successfully recovered from the condition following the administration of these medications.
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