Evidence map›Paper›PMID 40443601›Full record

ArticleCureus2025

Sudden Death Due to Hypercoagulability in a Patient With Pancreatic Cancer and Diabetic Ketoacidosis.

Esther Park, Milenko T Petrovic, Nidal Shah, Rahul Sharma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Esther ParkPathology, University of Arkansas for Medical Sciences, Little Rock, USA.
Milenko T PetrovicPathology, University of Arkansas for Medical Sciences, Little Rock, USA.
Nidal ShahInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Rahul SharmaInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is a significant contributor to cancer-related mortality, with an increasing incidence linked to an aging population. A rare complication of pancreatic cancer is diabetic ketoacidosis (DKA), which arises from the tumor's impairment of insulin production. DKA can also present alongside other challenges such as malnutrition and hypercoagulability. This study describes a 67-year-old female patient with a past medical history of type 2 diabetes who presented with DKA and was later diagnosed with a pancreatic mass suggestive of malignancy. She developed multiple venous thrombi and subsequent pulmonary emboli, leading to sudden death. Autopsy revealed extensive occlusive thrombi and ischemic changes, emphasizing the potentially life-threatening interactions between DKA, malignancy-associated hypercoagulability, and metabolic derangements of pancreatic cancer. This study reinforces the need for careful monitoring and management of thrombotic events in patients with multiple comorbidities.

Indexed as

acute pulmonary embolismcode statusdiabetic ketoacidosis (dka)endoscopyfatal outcomemalignancy-associated hypercoagulabilitypancreatic cancertype 2 diabetes mellitus

Identifiers

PMID40443601
PMCPMC12119977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.