Evidence map›Paper›PMID 40443524›Full record

ArticleFrontiers in medicine2025

The EULAR-OMERACT joint-level scoring of ultrasound synovitis demonstrates good construct validity when tested at the patient-level in comparison with measures of disease activity and joint damage in patients with rheumatoid arthritis.

York Kiat Tan, Julian Thumboo

Abstract read
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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

York Kiat TanDepartment of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.
Julian ThumbooDepartment of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Patient-level ultrasound joint inflammation outcomes, derived from the European Alliance of Associations for Rheumatology-Outcome Measures in Rheumatology (EULAR-OMERACT) joint-level scoring of elementary components and the combined score (CS), were compared with measures of disease activity and joint damage in patients with rheumatoid arthritis (RA). Methods: Clinical joint assessment and a 22-joint (bilateral hands/wrists) ultrasonography were performed independently during the same patient study visit. Patient-level ultrasound joint inflammation outcomes [total power Doppler (PD) score, total grayscale (GS) score, total CS, number of joint(s) with CS ≥ 2 (at least moderate synovitis), and number of joint(s) with ultrasound synovitis defined as PD > 0 or GS ≥ 2] derived from the EULAR-OMERACT joint-level scoring system were correlated with Clinical Disease Activity Index (CDAI), 28-joint disease activity score (DAS28), and ultrasound-detected joint damage, i.e., total bone erosion score (TBES). The relationship between the variables was studied using simple linear regression. Results: A total of 83 RA patients underwent scanning of 1,826 joints in this cross-sectional study. All patient-level ultrasound joint inflammation outcomes showed significant correlations ( Conclusion: Patient-level ultrasound joint inflammation outcomes, derived from the EULAR-OMERACT joint-level scoring system, showed good construct validity when compared to both disease activity and joint damage in patients with RA.

Indexed as

bone erosionjointsrheumatoid arthritissynovitisultrasound

Identifiers

PMID40443524
PMCPMC12119249

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