Evidence map›Paper›PMID 40443510›Full record

ArticleFrontiers in medicine2025

Development and validation of a nomogram for predicting hemoptysis recurrence in cystic bronchiectasis patients following bronchial artery embolization.

Yuxin Duan, Weifan Sui, Zefeng Cai, Yimao Xia, Jianyun Li, Jianhua Fu

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yuxin DuanDepartment of Interventional Radiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Weifan SuiDepartment of Interventional Radiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Zefeng CaiDepartment of Interventional Radiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Yimao XiaDepartment of Interventional Radiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Jianyun LiDepartment of Interventional Radiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Jianhua FuDepartment of Interventional Radiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hemoptysis is a life-threatening manifestation frequently observed in patients with cystic bronchiectasis (CB), a radiologically defined subtype of bronchiectasis. Bronchial artery embolization (BAE) is widely employed as an effective interventional therapy for controlling hemoptysis. Despite its clinical utility, the risk of recurrence remains high, particularly in patients with CB. Currently, no reliable predictive model specifically targeting CB-related hemoptysis recurrence following BAE has been established, highlighting the need for a tailored prognostic tool in this population. Objective: This study aimed to develop and validate a model to predict the recurrence of hemoptysis in CB patients following BAE, enabling individualized clinical management and prevention strategies. Methods: A retrospective study was conducted on 111 CB patients who underwent BAE between January 2015 and June 2020. Clinical, radiological, and laboratory data were collected for analysis. Least absolute shrinkage and selection operator (LASSO) regression was applied to identify relevant predictive variables, followed by multivariable Cox proportional hazards regression to determine independent prognostic factors. Based on these predictors, a nomogram was constructed. Its performance was assessed using the concordance index (C-index), receiver operating characteristic (ROC) curves, area under the curve (AUC), calibration plots, and decision curve analysis (DCA). Results: Five independent predictors were identified: history of hemoptysis (HR = 3.42, 95% CI: 1.64-7.12, Conclusion: The nomogram is a reliable tool for predicting hemoptysis recurrence in CB patients after BAE. It facilitates early identification of high-risk patients, enabling timely, targeted interventions and improved outcomes.

Indexed as

bronchial artery embolizationcystic bronchiectasishemoptysisnomogramrecurrence prediction

Identifiers

PMID40443510
PMCPMC12119253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.