Evidence map›Paper›PMID 40443223›Full record

ArticleJournal of microbiology and biotechnology2025

Related Mechanism of Limonene Improves LPS-Induced Neuroinflammation.

Yingjuan Jiang, Geng Liu, Qingqing Liu, Lanyue Zhang, Yanping Tan, Junlin Cen, Yan Zhao, Aiguo Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingjuan JiangDepartment of General Medicine, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, P.R. China.
Geng LiuDepartment of General Medicine, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, P.R. China.
Qingqing LiuSchool of Public Health, Southwest Medical University, Sichuan 646000, P.R. China.
Lanyue ZhangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, P.R. China.
Yanping TanDepartment of Neurology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, P.R. China.
Junlin CenDepartment of General Medicine, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, P.R. China.
Yan ZhaoDepartment of General Medicine, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, P.R. China.
Aiguo LiGuangzhou Institute of Traumatic Surgery, Department of Orthopedics, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limonene, a component of volatile oils extracted from citrus plants, is known traditionally to treat inflammation. However, the anti-neuroinflammation efficacy and mechanism remain unclear. In this study, lipopolysaccharide was used as a neuroinflammatory inducer to investigate the mechanism of limonene in combating neuroinflammation in mice. Gas chromatography-mass spectrometry (GCMS) was used to identify the main components of

Indexed as

Anti-Inflammatory AgentsInflammationLimoneneLipopolysaccharidesNeuroinflammatory DiseasesAnimalsCell LineCerebral CortexCitrusCytokinesDisease Models, AnimalGas Chromatography-Mass SpectrometryGlial Fibrillary Acidic ProteinHippocampusMaleMiceAnti-Inflammatory AgentsCytokinesGlial Fibrillary Acidic ProteinLimoneneLipopolysaccharidesOils, VolatileLimonenelipopolysaccharideneuroinflammationtranscriptomics

Identifiers

PMID40443223
PMCPMC12149406

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.