ArticleEuropean journal of pain (London, England)2025
Reference Values of Joint-Specific Pressure Pain Thresholds in Healthy Male Individuals: A Retrospective Study.
Article in European journal of pain (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Time-dependent microvascular and analgesic responses to cold compression in healthy adults: identifying the optimal cooling duration for recovery.European journal of applied physiology · 2026Trial
- Trial
- Reference ranges and influencing factors of pressure pain threshold in Chinese patients with knee osteoarthritis.Annals of medicine · 2026Article
- Reliability and standard error of measurement of pressure pain thresholds at articular landmarks.British journal of pain · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPressure pain thresholds (PPT) are a component of Quantitative Sensory Testing and are used to assess mechanical pain sensitivity. Joint-specific PPT measurements are relevant because many joint disorders involve altered pain processing at and around joints. This study aims to establish such reference values that might contribute to evaluate deviations in pain sensitivity in specific patient populations.
methodsThis study retrospectively analysed PPT data from 407 healthy male individuals. Pressure was applied in a standardised manner using an algometer at eight anatomical landmarks: bilaterally at the elbow, knee and ankle joints, as well as the sternum and forehead. Percentile-based, landmark-discriminative normative data were calculated for PPT in general and segmented for age, BMI and mean subjective pain over 4 weeks.
resultsMedian (IQR) PPT values (N/cm
conclusionThis study provides normative joint-specific PPT values in healthy male individuals, offering reference values for both clinical and research applications. These values can assist in interpreting PPT measured in clinical settings and in identifying abnormal pain sensitivity. SIGNIFICANCE STATEMENT: Pressure pain thresholds are an important measure in Quantitative Sensory Testing, yet comprehensive normative data for joint-specific PPT in healthy individuals have been lacking. This study establishes reference values across multiple anatomical landmarks, providing a critical benchmark for evaluating pain sensitivity deviations in musculoskeletal disorders. These findings enhance the interpretation of PPT measurements, supporting improved pain assessment and diagnostic accuracy.
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