ArticlePlant communications2025
BBX24 and BBX25 antagonize the function of thermosensor ELF3 to promote PIF4-mediated thermomorphogenesis in Arabidopsis.
Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Antagonistic regulation of PIF4 and HY5 activity by BBX28 regulates thermomorphogenesis.Science advances · 2026Article
- Temperature regulation in plants: From molecular mechanisms to climate-resilient crop improvement.Journal of integrative plant biology · 2026Review
- Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience.The New phytologist · 2026Review
- Oligomerization-competent PIF4 drives thermomorphogenesis through functional redundancy in transactivation and DNA binding.Nature communications · 2026Article
- CUL3Science advances · 2026Article
- PIF4-mediated thermomorphogenesis relies on its oligomerization ability, not DNA-binding or transactivation activity.Research square · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Temperature is a crucial environmental cue that governs plant growth and adaptation in natural habitats. PHYTOCHROME INTERACTING FACTOR 4 (PIF4) functions as a central regulator promoting thermomorphogenesis in Arabidopsis. An understanding of its precise regulation is essential for optimal thermomorphogenic growth. Here, we identified two BBX proteins, BBX24 and BBX25, as novel components of the PIF4-mediated thermosensory pathway that promote growth at elevated temperatures. Single and double mutants of bbx24 and bbx25 exhibit moderate to strong temperature-insensitive hypocotyl and cotyledon growth. Elevated temperatures induce BBX24 and BBX25 mRNA expression and protein accumulation. Genetic and biochemical analyses reveal that BBX24 and BBX25 enhance PIF4-mediated thermosensory growth by counteracting ELF3, a key component of the evening complex. Whereas ELF3 represses BBX24 and BBX25 gene expression at low ambient temperatures during the evening, the inhibition of ELF3 activity under elevated temperatures increases BBX24 and BBX25 activity. Moreover, BBX24 and BBX25 suppress ELF3 function through direct physical interaction, likely relieving its repression of PIF4 and enhancing thermomorphogenesis. These findings identify the ELF3-BBX24/BBX25-PIF4 axis as a key regulatory module controlling plant growth and development in response to temperature cues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.