Evidence map›Paper›PMID 40443004›Full record

ReviewJournal of managed care & specialty pharmacy2025

Clinical evaluation of zavegepant for the acute treatment of migraine.

Huiqiao Fan, Janette Wadolowski, Ryan Shan, Gianni J Contrera, Christina M Polomoff

Abstract readLetterReview
In one paragraph

Review in Journal of managed care & specialty pharmacy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huiqiao FanUniversity of Connecticut School of Pharmacy, Storrs.
Janette WadolowskiUniversity of Connecticut School of Pharmacy, Storrs.
Ryan ShanUniversity of Connecticut School of Pharmacy, Storrs.
Gianni J ContreraUniversity of Connecticut School of Pharmacy, Storrs.
Christina M PolomoffUniversity of Connecticut School of Pharmacy, Storrs.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zavegepant is the first intranasal calcitonin gene-related peptide receptor antagonist approved for the acute treatment of migraine and offers a new nonoral option for patients. This article reports the findings of a comprehensive literature review to assess zavegepant's safety and effectiveness. Evidence synthesis involved reporting findings from clinical trials and evaluating comparative effectiveness. This review was prepared by the University of Connecticut School of Pharmacy Academy of Managed Care Pharmacy (AMCP) Student Chapter. The student author group won the AMCP National Pharmacy and Therapeutics competition for their zavegepant product review in March 2024.

Indexed as

Calcitonin Gene-Related Peptide Receptor AntagonistsMigraine DisordersAdministration, IntranasalHumansTreatment OutcomeCalcitonin Gene-Related Peptide Receptor Antagonists

Identifiers

PMID40443004
PMCPMC12123197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.