Evidence map›Paper›PMID 40442921›Full record

SynthesisJournal of comparative effectiveness research2025

Comparative safety of B/F/TAF versus other antiretroviral therapy regimens for treatment-naïve people with HIV-1: a systematic literature review and network meta-analysis.

Tristan Curteis, Lucy A Eddowes, Megan Chen, Bhumi Gandhi-Patel, Andrei Karlsson, Hannah Luedke, Manon Rubinstein, Mathias Hempfling, Ernesto G Scerpella, Paresh Chaudhari and 1 more

Abstract readNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of comparative effectiveness research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tristan CurteisCostello Medical, Manchester, UK.
Lucy A EddowesCostello Medical, Bristol, UK.
Megan ChenGilead Sciences Inc, Foster City, CA, USA.
Bhumi Gandhi-PatelGilead Sciences Inc, Foster City, CA, USA.
Andrei KarlssonCostello Medical, London, UK.
Hannah LuedkeCostello Medical, London, UK.
Manon RubinsteinCostello Medical, London, UK.
Mathias HempflingCostello Medical, Manchester, UK.
Ernesto G ScerpellaGilead Sciences Inc, Foster City, CA, USA.
Paresh ChaudhariHEOR Consultant, SimulStat Incorporated, Solana Beach, CA, USA.
James JarrettGilead Sciences Inc, Foster City, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAnti-HIV AgentsEmtricitabineHIV InfectionsTenofovirAlanineAmidesBayes TheoremHeterocyclic Compounds, 3-RingHeterocyclic Compounds, 4 or More RingsHIV-1PiperazinesPyridonesAdenineAlanineAmidesAnti-HIV AgentsbictegravirEmtricitabineHeterocyclic Compounds, 3-RingHeterocyclic Compounds, 4 or More RingsPiperazinesPyridonesTenofovirtenofovir alafenamideantiretroviral therapyHIV-1network meta-analysissafety and tolerabilitysystematic literature review

Identifiers

PMID40442921
PMCPMC12224115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.