Evidence map›Paper›PMID 40442831›Full record

SynthesisJournal of health, population, and nutrition2025

Prevalence of osteoporosis in patients with inflammatory bowel disease: a systematic review and meta-analysis.

Mobin Marzban Abbas Abadi, Seyedeh Tahereh Emadian, Mohammad Zamani, Majid Khalilizad

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  11. The association between theFrontiers in genetics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mobin Marzban Abbas AbadiDepartments of Orthopedic and Trauma Surgery, Babol University of Medical Sciences, Babol, Iran.
Seyedeh Tahereh EmadianNon-communicable Pediatric Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Mohammad ZamaniDigestive Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Majid KhalilizadMobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Ganjafrooz Street, Babol, Mazandaran, Iran. m.khalilzad@mubabol.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough prior studies alluded to the association between inflammatory bowel disease (IBD) and osteoporosis, the exact prevalence of osteoporosis in this patient population remains variably reported. Therefore, we aimed to systematically explore the overall prevalence of osteoporosis in patients with IBD.

methodsWe searched in Embase, PubMed, and Scopus, from the inception until 31 May 2024. We included studies that reported cross-sectional data on the prevalence of osteoporosis in at least 100 adult (≥ 18 years) patients with IBD. We combined the data extracted from the eligible studies to obtain pooled estimates using a random-effects model.

resultsA total of 24 articles were included, comprising 417,298 patients with IBD. Our analysis showed that the overall pooled prevalence of osteoporosis in IBD patients was 12.2% (95% confidence interval [CI]: 9.1-15.3; I

conclusionThere is a significant prevalence of osteoporosis in patients with IBD, though variations by disease type and sex are not probably observed. We witnessed high heterogeneity among the studies. Tailored approaches are warranted for osteoporosis screening and management in this patient population.

Indexed as

Inflammatory Bowel DiseasesOsteoporosisAdultCross-Sectional StudiesFemaleHumansMalePrevalenceRisk FactorsInflammatory bowel diseaseOsteoporosisSystematic review

Identifiers

PMID40442831
PMCPMC12123853

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.