Evidence map›Paper›PMID 40442791›Full record

Observational studyJournal of orthopaedic surgery and research2025

Prognostic factors of selective nerve root block under fluoroscopic guidance for the treatment of young patients with lumbar disc herniation and its role in preventing surgery.

Leilei Gao, Hui Xiao, Rui Ma, Jun Liu, Xiaoxia Huang, Luyao Li, Kai Ye, Tao Liu, Yong Teng

Abstract readObservational Study
In one paragraph

Observational study in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Leilei Gao *Graduate School of Xinjiang Medical University, Urumqi, Xinjiang, P. R. China.
Hui XiaoDepartment of Orthopedics, General Hospital of Xinjiang Military Command, Urumqi, Xinjiang, P. R. China.
Rui MaDepartment of Orthopedics, General Hospital of Xinjiang Military Command, Urumqi, Xinjiang, P. R. China.
Jun LiuGraduate School of Xinjiang Medical University, Urumqi, Xinjiang, P. R. China.
Xiaoxia HuangGraduate School of Xinjiang Medical University, Urumqi, Xinjiang, P. R. China.
Luyao LiDepartment of Orthopedics, General Hospital of Xinjiang Military Command, Urumqi, Xinjiang, P. R. China.
Kai YeDepartment of Orthopedics, General Hospital of Xinjiang Military Command, Urumqi, Xinjiang, P. R. China.
Tao LiuThe First Affiliated Hospital, Air Force Medical University, Xi'an, P. R. China. docliutao@126.com.
Yong TengDepartment of Orthopedics, General Hospital of Xinjiang Military Command, Urumqi, Xinjiang, P. R. China. orthtengyong@163.com.

Funding

The Karakorun Foundation Top Talent Program 23bj02The Natural Science Foundation of Xinjiang Uygur Autonomous Region 2023D01C93
6 · The paper itself

Abstract

backgroundAs a transitional treatment between conservative treatment and surgical treatment for lumbar disc herniation (LDH), selec tive nerve root block (SNRB) has attracted increasing attention recently. The objective of this study was to evaluate the efficacy and prognostic factors of SNRB in young patients with LDH.

methodsA prospective observational cohort study was employed. A total of 134 patients with LDH who received SNRB treatment in our hospital from January 2023 to August 2023 were selected and divided into a recurrence group and a nonrecurrence group according to whether they experienced recurrence after SNRB. The demographic characteristics, clinical and imaging data and SNRB-related information were compared between the two groups. Multivariate logistic regression was used to analyze the factors influencing symptom recurrence after SNRB surgery.

resultsSurgery was avoided in 95.522%, 86.567%, 78.358% and 64.925% of the patients at 2 weeks, 3 months, 6 months and 12 months after SNRB treatment, respectively. Multivariate logistic regression analysis revealed that a disease course of ≥ 3 months (OR = 6.031, 95% CI: 2.592-14.035, P = 0.001) was an independent risk factor for postoperative recurrence of SNRB, and extreme lateral protrusion (OR = 0.273, 95% CI: 0.078-0.956, P = 0.042) and the HIZ sign (OR = 0.200, 95% CI: 0.057-0.702, P = 0.012) were protective factors against postoperative recurrence of SNRB.

conclusionsThe curative effect of SNRB in the treatment of young patients with LDH is significant. A disease course of ≤ 3 months, far-lateral protrusion and the HIZ sign are predictors of good outcomes. In addition, SNRB combined with medication and physical therapy is recommended as an alternative to surgery for patients who do not have acute surgical indications.

Indexed as

Intervertebral Disc DisplacementLumbar VertebraeNerve BlockSpinal Nerve RootsAdultCohort StudiesFemaleFluoroscopyHumansMalePrognosisProspective StudiesRecurrenceTreatment OutcomeYoung AdultFluoroscopic guidanceLumbar disc herniationPrognostic factorsSelective nerve root block

Identifiers

PMID40442791
PMCPMC12121116

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.