ArticleBMC oral health2025
Evaluation of mandibular bone quality with respect to enzyme inducement potential of antiepileptic drugs via fractal analysis.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Individuals diagnosed with epilepsy: a fractal analysis and radiomorphometric evaluation.BMC oral health · 2026Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundEpilepsy is a neurological disorder characterized by recurrent seizures and antiepileptic drug (AED) therapy is used in treatment. AED therapy have significant adverse effects as osteopenia, osteoporosis and reduced bone mineral density (BMD). PURPOSE: The objective of this study is to evaluate the potential effects of AEDs on the trabecular of the mandible by classifying the drugs according to their ability to induce enzymes and comparing them with those of healthy people using fractal analysis. MATERIALS AND
methodsIn this study, dental records of 70 patients (35 AED users and 35 control group) were used. Additionally, the study group was further investigated for the presence of enzyme inducing mechanism. Fractal analysis (FA), panoramic mandibular index (PMI), mandibular cortical width (MCW), and Klemetti index (KI) measurements were performed on panoramic radiographs.
resultsNo statistically significant difference was observed between the study and control groups in terms of FA results and MCW, PMI and KI. There was not a statistically significant difference between AED subgroups, either.
conclusionThe findings of this study indicate that the microstructural changes and panoramic morphometric indices of the mandible of AED users do not differ from those observed in healthy subjects. CLINICAL TRIAL NUMBER: Not applicable.
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