Observational studyBMC pediatrics2025
Deterioration of nutritional status at discharge in critically ill children with appropriate BMI and its association with clinical outcomes: a prospective observational study.
Observational study in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo determine how nutritional status changes during critical illness in children with age-appropriate BMI at admission and evaluate its impact on clinical outcomes.
methods70 subjects with age-appropriate BMI between 2 and 12 years were included in the study. The Z-scores (weight, height, BMI) MUMC, Subjective Global Nutritional Assessment (SGNA), and nutritional intake were calculated on admission and discharge. The relationship between changes in nutritional status with clinical outcomes were assessed.
resultsThis study includes samples that all were well-nourished based on Z-scores of BMI and weight. However, based on the SGNA 45% were undernourished. All anthropometric variables decreased significantly at the time of discharge. Regression analysis adjusted by age, number of Number of organs with dysfunction at PICU admission, PIM2, and hospital days before ICU admission showed that reduced BMI-for-age was significantly associated with prolonged PICU stay (B = 2.883; CI: 1.813-3.952) and an increased duration of mechanical ventilation (B = 1.541; CI: 0.493-2.588). Every 1 cm decrease in MUAC was associated with a 3.5-fold increase in mortality risk (OR = 3.527; CI: 1.518-9.972). Delayed initiation of nutrition was significantly correlated with a prolonged PICU stay (B = 1.395; CI: 0.518-2.271) and increased duration of mechanical ventilation (B = 0.861; CI: 0.132-1.589). Malnutrition at admission, as assessed by SGNA, was also associated with longer PICU stay (B = 1.739; CI: -0.154- 2.294). Furthermore, increased protein intake during the first week was significantly associated with decrease in the need to mechanical ventilation (OR = 0.824; CI: 0.682-0.995).
conclusionA comprehensive nutritional assessment should be performed for children admitted with an appropriate BMI, feeding should not be delayed, adequate protein intake should be ensured, and indicators such as MUAC and SGNA should be considered in addition to BMI. These measures can improve clinical outcomes and reduce complications during the PICU stay.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.