Evidence map›Paper›PMID 40442625›Full record

ArticleBMC public health2025

From parental education to under-5 mortality: how antenatal care and hand hygiene mediate the pathway mechanisms.

Tapas Mazumder, Itismita Mohanty, Danish Ahmad, Theo Niyonsenga

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tapas MazumderHealth Research Institute, Faculty of Health, University of Canberra, Canberra, ACT, 2617, Australia. tapas.mazumder@canberra.edu.au.
Itismita MohantyHealth Research Institute, Faculty of Health, University of Canberra, Canberra, ACT, 2617, Australia.
Danish AhmadHealth Research Institute, Faculty of Health, University of Canberra, Canberra, ACT, 2617, Australia.
Theo NiyonsengaHealth Research Institute, Faculty of Health, University of Canberra, Canberra, ACT, 2617, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReducing the under-5 mortality rate (U5MR) to as low as 25/1000 live births globally by 2030 to reach the sustainable development goal (SDG) 3.2.1 appears to be a race against time. Amidst this situation, Bangladesh experienced stagnancy in U5MR at the beginning of the SDG era. While a comprehensive understanding of this stagnancy is crucial, research on stagnancy is scant and limited to investigating the direct effects of the key predictors. Therefore, building on the existing evidence, this research investigated the effect of one of the key predictors, parental education, on under-5 mortality (U5M) mediated through antenatal care (ANC) and the availability of hand washing stations.

methodsThis study conducted weighted mediation analyses using the Bangladesh Demographic and Health Survey data from 2011, 2014 and 2017-18, with sample sizes 4,658, 4,367, and 4,826, respectively, and estimated a generalised structural equation model. The "nlcom" post-estimation command of STATA was used to obtain the direct effects (coefficients), which were then multiplied to estimate the indirect effects for the indirect parallel and sequential pathways. The indirect effects were added to obtain the total indirect effect, which was added to the direct effect of education to estimate the total effect of education.

resultsThis study reveals inconsistent parallel and sequential mediation of parental education's effect across the three surveys. The direct effect of education on U5M reduced over time. The total (parallel and sequential combined) mediated effects of either parent's education on U5M were negative (reduced U5M risk). While the mediated effect of mother's education on U5M was not significant, the mediated effect of father's education was significant in 2011. The total effect of education (direct and indirect combined) on U5M was negative (reduced U5M risk) and significant in 2011. However, the effect reduced over time and changed direction in 2017-18. Since 2011, the effects decreased and changed direction to become positive (increased U5M risk) in 2017-18. Due to the weakening direct effect of education and the opposite nature of the indirect effect, the indirect effect of education appeared to be greater than the total effect in 2014 and 2017-18. In 2011, approximately 50% of the total effect of either parent's education was mediated. However, in 2014 and 2017-18, the proportions were greater than 100%, except for the proportion of the mediated effect of father's education in 2014.

conclusionsThis study reports a weakening and inconsistent mediated effect of both parents' education on U5M. Using existing literature, it also justifies that improving the quality of education and ANC could more effectively reduce U5M to achieve SDG 3.2.1. To improve the quality of education, this study recommends updating the school curriculum with a greater emphasis on maternal and child health education. To improve the quality of ANC, it is recommended that the mandatory use of ANC cards be strictly monitored.

Indexed as

Child MortalityEducational StatusHand HygieneInfant MortalityParentsPrenatal CareAdultBangladeshChild, PreschoolFemaleHumansInfantInfant, NewbornMalePregnancyYoung AdultAntenatal careEducationHandwashingMediation analysisStagnancyUnder-5 mortality

Identifiers

PMID40442625
PMCPMC12121073

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.