Evidence map›Paper›PMID 40442623›Full record

Observational studyBMC public health2025

COVID-19 disease severity in language minorities in Finland: an observational population-based register study.

Juulia Pynnönen, Heli Salmi, Mitja Lääperi, Anu Kantele, Ville Holmberg

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juulia PynnönenDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Heli SalmiDepartment of Anaesthesia and Intensive Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Mitja LääperiDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Anu KanteleDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ville HolmbergDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. ville.holmberg@hus.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMigrants and ethnic minority populations appear to have experienced a disproportionate burden of the coronavirus disease 2019 (COVID-19) pandemic. In Finland, a foreign first language is often considered an indicator of foreign ethnicity. We investigated whether hospitalized patients with a foreign first language presented with a more severe COVID-19 upon admission to specialized health care, and if they had a similar in-hospital course of disease compared with those with a domestic first language.

methodsWe conducted a retrospective observational population-based register study, including all patients with confirmed COVID-19 infection admitted to specialized health care and intensive care units (ICUs) in the capital province of Finland between 27 February and 3 August 2020. We examined first values, peak values, and changes in laboratory parameter elevation during hospitalization among different language groups. Studied biomarkers included creatinine, alanine aminotransferase (ALAT), fibrin D-dimer, leukocyte count, thrombocytes, C-reactive protein (CRP), and lactate dehydrogenase (LDH).

resultsFirst language was registered for 614 (94.9%) patients admitted to specialist care, of whom 131 (21.3%) had a foreign first language. Those with a foreign first language were younger (median 49, IQR 36.5-57, versus 62, 50-75.5, years, p < 0.001) and exhibited smaller changes in CRP (22.5, IQR 0-104.75 versus 52, IQR 7.25-125, p = 0.031). After adjustment for age and sex, none of the differences remained significant. A foreign first language did not impact the risk of ICU admission (20.1% versus 21.4%, p = 0.81). Peak leukocyte count, change in leukocyte count, and all CRP variables were the most significant indicators of ICU admission (p < 0.001 for all) and behaved similarly across language groups.

conclusionsCRP and leukocyte count were the most reliable indicators of more severe COVID-19 disease presentation and ICU admission. Although those with a foreign first language were overrepresented in COVID-19 related hospitalizations, we found no significant differences in laboratory findings based on first language, implying that disease severity among hospitalized patients did not differ between language minorities and the rest of the population.

Indexed as

COVID-19LanguageMinority GroupsAdultAgedFemaleFinlandHospitalizationHumansIntensive Care UnitsMaleMiddle AgedRegistriesRetrospective StudiesSeverity of Illness IndexCOVID-19EthnicityLaboratory parameterLanguageMigrantMinoritySARS-CoV-2

Identifiers

PMID40442623
PMCPMC12121010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.