Evidence map›Paper›PMID 40442616›Full record

SynthesisBMC anesthesiology2025

Comparison of non-intubated and intubated video-assisted thoracoscopic surgery for perioperative complications-a systematic review and meta-analysis.

Diaofeng Zhang, Jie Wu, Yihan Yang, Ruifang Pu, Zixiao Liu, Yun Li, Wei Deng, Jiale Wang, Bo Hou, Zengcai Ge and 3 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Diaofeng Zhang *Department of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Jie Wu *Department of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Yihan YangDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Ruifang PuDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Zixiao LiuDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Yun LiDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Wei DengDali University, Dali, Yunnan Province, China.
Jiale WangDepartment of Orthopedics, Yuanmou County First People's Hospital, Chuxiong, Yunnan Province, China.
Bo HouDepartment of Thoracic Surgery, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Yunnan Province, Qujing, China.
Zengcai GeDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Jiao GaoDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China.
Jiangang LiDepartment of Anesthesiology, Qujing First People's Hospital: Kunming Medical University Affiliated Qujing Hospital, Qujing, Yunnan Province, China. 77684698@qq.com.
Liming ChengDepartment of Anesthesiology, Kunming Children's Hospital, Kunming, Yunnan Province, China. medcheng@163.com.

Funding

Kunming Medical University Affiliated Qujing Hospital Level Project Fund 2023YJKTY07Scientific Research Fund of Yunnan Provincial Department of Science and Technology and Kunming Medical University Joint Project 202401AY070001-346
6 · The paper itself

Abstract

backgroundNon-intubated video-assisted thoracic surgery (NIVATS) avoids lung injury and intubation-related complications from mechanical ventilation, but the intraoperative safety and postoperative recovery quality of NIVATS remain controversial. Consequently, we systematically assessed the viability and safety of non-intubated video-assisted thoracic surgery (NIVATS) in comparison to intubated video-assisted thoracic surgery (IVATS). These findings provide evidence for optimizing anesthetic and surgical decision-making.

methodsPubMed, Web of Science, Embase, Cochrane Library, OVID, and Google Scholar were queried from their establishment until October 2024. We included eligible studies that compared non-intubated anesthesia with intubated anesthesia for video-assisted thoracoscopic surgery for thoracic conditions. Following the evaluation of bias risk in these randomized controlled trials (RCTs), a meta-analysis was conducted using Review Manager (Manager 5.4).

resultsNineteen randomized controlled trials were incorporated into the study. NIVATS demonstrated a reduced length of hospital stay, feeding time, and chest-tube dwell time compared to intubated methods. IVATS groups, hypoxemia exhibited a reduced incidence, but perioperative cough and perioperative arrhythmias revealed no statistically significant differences between IVATS and NIVATS groups. The NIVATS groups exhibited a significantly reduced risk compared to the IVATS groups for postoperative pulmonary complications (PPCs), postoperative nausea and vomiting (PONV), and sore throat.

conclusionsNIVATS avoid complications associated with intubation and are able to accelerate patient recovery to a certain extent. Although NIVATS carries intraoperative safety risks, careful patient selection can mitigate these risks.

Indexed as

Intraoperative ComplicationsIntubation, IntratrachealPostoperative ComplicationsThoracic Surgery, Video-AssistedHumansLength of StayRandomized Controlled Trials as TopicLength of hospital stayMeta-analysisNon-intubated anesthesiaPPCsThoracic surgeryVATS

Identifiers

PMID40442616
PMCPMC12121218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.