ArticleBMC plant biology2025
AHL26, an AT-hook gene, negatively regulates hypocotyl growth and flowering time in Arabidopsis thaliana.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The AT-HOOK MOTIF CONTAINING NUCLEAR LOCALIZED gene promotes somatic embryogenesis and polyploidy formation in Liriodendron hybrids.Plant cell reports · 2026Article
- Single-Cell Transcriptome Atlas and Dynamic Regulatory Mechanisms of Anther Development in Alfalfa (Medicago sativa L.).Plant biotechnology journal · 2025Article
- Genome-Wide Analysis of the AT-Hook Gene Family inPlants (Basel, Switzerland) · 2025Article
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4 authors.
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Abstract
backgroundThe AT-HOOK MOTIF CONTAINING NUCLEAR LOCALIZED (AHL) gene family in Arabidopsis contains 29 members, which evolved into two phylogenetic clades. Genes from this family play a role in several biological processes, but most of the members' functions remain unknown.
resultsHere, we provide evidence that AHL26, a clade-a protein, negatively regulates hypocotyl growth and flowering time in Arabidopsis. Analysis of transgenic plants expressing an AHL26:AHL26:GUS translational fusion driven by 1.9 KB of the endogenous AHL26 promoter displayed GUS activity in the hypocotyl and apical meristem of light-grown seedlings. The overexpression of AHL26 resulted in the inhibition of hypocotyl growth and delayed flowering. However, the overexpression of a dominant-negative AHL26 with mutation in AT-hook motif, resulted in early flowering and longer hypocotyls than the WT and over-expression transgenic lines suggesting genetic redundancy between AHL26 and other AHL genes. Transcriptome analysis showed that the regulation of flowering time in AHL26 over-expression and dominant-negative mutants results from regulating flowering-related genes and pathways.
conclusionOur study highlights the significant role of AHL26 in hypocotyl growth and flowering time regulation. We further demonstrate that AHL26 regulates hypocotyl length in a light-dependent manner. Through transcriptomic analysis, we also show that the delayed flowering phenotype in our AHL26 over-expression plants is due to the negative regulation of flowering-promoting genes such as FT. Furthermore, transcriptome analysis provides insight into the biological processes and pathways through which AHL26 influences the control of flowering time.
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