ArticleBMC cardiovascular disorders2025
Microcirculatory dysfunction in patients with acute anterior myocardial infarction combined with new complete right bundle branch block.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Alternating Bundle Branch Block Despite a Patent Stent in Late-Presenting Extensive Anterior STEMI.JACC. Case reports · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
objectiveThis study sought to investigate clinical characteristics of acute anterior ST-segment elevation myocardial infarction (STEMI) patients complicated by new complete right bundle branch block (CRBBB) and evaluate the occurrence of microcirculatory dysfunction post-percutaneous coronary intervention (PCI).
methodsRetrospective analysis was conducted on 261 patients with acute anterior STEMI, differentiating 40 with concurrent new CRBBB (CRBBB group) from 221 without (no-CRBBB group). Data on demographics and hospitalization were collected, and clinical features and prognoses were compared. Post-PCI microcirculatory function was further characterized using coronary angiography-derived index of microcirculatory resistance (caIMR), thrombolysis in myocardial infarction (TIMI) grade flow, corrected TIMI flow frame count (CTFC) of the infarct-related artery, and ST segment regression in electrocardiograph (STR).
resultsAge, Killip class, GLUC, TG, HDL, BUN, GFR, AST, ALT, WBC, TNI at admission significantly differed between groups (P < 0.05). Incidences of in-hospital major adverse cardiovascular events and LVEF showed significant disparities (P < 0.05). The CRBBB group exhibited higher CaIMR, lower TIMI flow, and STR (P < 0.05). Multivariate analysis indicated TIMI ≤ grade 2 (OR = 6.833, 95% CI: 1.009 ~ 46.287, P = 0.049), STR ≥ 50% (OR = 0.176, 95% CI: 0.051 ~ 0.606, P = 0.006), CTFC (OR = 1.079, 95% CI: 1.009 ~ 1.155, P = 0.027), and caIMR (OR = 1.120, 95% CI: 1.059 ~ 1.185, P < 0.001) were independently linked to new onset of CRBBB. Complicated of new CRBBB was strongly associated with elevated CaIMR in anterior STEMI patients. (OR = 5.065, 95% CI:1.793-14.308, P = 0.002).
conclusionIn patients with acute anterior STEMI, those with new CRBBB are at an increased likelihood of experiencing microcirculatory dysfunction.
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