Evidence map›Paper›PMID 40442533›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

The efficacy of psychosocial interventions on anxiety and depression in cancer caregivers: a network meta-analysis.

Chunyu Kao, Di Wang, Weihua Pan, Lijuan Hou, Peng Zhou, Ziyu Zhang, Lixiang Yu, Fei Wang, Liyuan Liu

Abstract readNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunyu Kao *Institute for Financial Studies, Shandong University, Jinan, China.
Di Wang *Institute for Financial Studies, Shandong University, Jinan, China.
Weihua PanMedical Management Service Center of Health Commission of Shandong Province, Jinan, China.
Lijuan HouHonghui Hospital, Xi'an Jiaotong University, Xi'an, China.
Peng ZhouDepartment of Breast Surgery, The Second Hospital of Shandong University, Jinan, China.
Ziyu ZhangSchool of Mathematics, Shandong University, Jinan, China.
Lixiang YuDepartment of Breast Surgery, The Second Hospital of Shandong University, Jinan, China.
Fei WangDepartment of Breast Surgery, The Second Hospital of Shandong University, Jinan, China.
Liyuan LiuMedical Management Service Center of Health Commission of Shandong Province, Jinan, China. liuliyuanforever@163.com.ORCID http://orcid.org/0000-0002-9862-7471

Funding

General programs of Natural Science Foundation of Shandong Province ZR2021MH243
6 · The paper itself

Abstract

backgroundCancer caregivers often face substantial psychosocial burdens, which can lead to significant anxiety and depression. This network meta-analysis aimed to evaluate the relative efficacy of various psychosocial interventions in alleviating these symptoms.

methodsFollowing PRISMA guidelines, we conducted a systematic literature search for randomized controlled trials (RCTs) that evaluated psychosocial interventions for cancer caregivers. Data were synthesized using a network meta-analysis to compare the effects of different interventions on anxiety and depression.

resultsA total of 35 trials involving 7 types of psychosocial interventions were included. Three interventions-meaning-centered psychotherapy (anxiety: MD =  - 5.48, 95% CI: - 8.46 to - 2.49; depression: MD =  - 5.13, 95% CI: - 8.27 to - 1.96), psychoeducation (anxiety: MD =  - 9.38, 95% CI: - 13.76 to - 4.94), and supportive therapy (anxiety: MD =  - 7.05, 95% CI: - 11.12 to - 3.05; depression: MD =  - 5.59, 95% CI: - 9.83 to - 1.36), showed significant efficacy in reducing anxiety and depression. Network meta-analysis indicated that these interventions were superior to control conditions in alleviating symptoms.

conclusionMeaning-centered psychotherapy, psychoeducation, and supportive therapy are particularly effective in reducing anxiety and depression among cancer caregivers. Our findings support the implementation of these psychosocial interventions as part of routine care.

Indexed as

AnxietyCaregiversDepressionNeoplasmsPsychosocial InterventionHumansPsychotherapyRandomized Controlled Trials as TopicAnxietyCancer caregiversDepressionNetwork meta-analysisPsychosocial interventions

Identifiers

PMID40442533
PMCPMC12122648

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.