ArticleBiological trace element research2026
Opposite Effects of Small and Large Diameter Selenium Nanoparticles on the Redox-Status and Survival of Cortical Cells in Toxic Models In Vitro.
Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Recent Advances in the Treatment of Thyroid Pathologies with Selenium-Containing Compounds, Nanoparticles and Nanocomplexes Based on Selenium and Selenoproteins.Biological trace element research · 2026Review
- Size-Dependent Differences in the Effects of Low-Dose Selenium Nanoparticles on Chronic Thioacetamide Toxicosis Accompanying HCC Progression in Mice.Biological trace element research · 2026Article
- Exogenous Selenoprotein V Induces Apoptosis in Murine Testicular Teratoma Cells via Mitochondrial Dysfunction and ROS Overproduction.Biomolecules · 2025Article
- Breaking the Alzheimer's Treatment Stalemate: Synergistic Application Strategies of Nanomaterials and Pharmaceutical Agents.Molecular neurobiology · 2025Review
- In Situ Synthesis of Non-Cytotoxic Tellurium Nanoparticle and Methacrylate Photopolymer Resin Composite with Antibacterial Activity.Polymers · 2025Article
- Therapeutic Effect of Selenium Nanoparticles, Sorafenib, and Selenium-Sorafenib Nanocomplex in the Lungs and Kidneys of Mice with TAA-Induced HCC.Biomolecules · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More and more studies are appearing devoted to the possibility of using nanotechnology in the prevention and treatment of neurodegenerative processes. This study aimed to develop a technology for obtaining small and large selenium nanoparticles (SeNPs) by laser ablation of a solid target. And also to study the effects of these different-sized nanoparticles on the physiology (calcium signalling, redox status, regulation of cell death) of cortical cells in culture in toxic models of ischemia-like conditions and glutamate excitotoxicity, primarily reflecting pathological processes in the brain during injuries, strokes, and neurodegenerative diseases. In the present study, a technology for obtaining SeNPs of different sizes is presented. Using molecular biology methods, fluorescence microscopy, viability assays, and measurement of ROS production in cortical cells, differences in the effects of SeNPs were revealed in acute and chronic experiments, in models of glutamate excitotoxicity and ischemia-like conditions. SeNPs with a size of 100 nm were most effective in suppressing cell death, modulating the cellular redox status, and Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.