Evidence map›Paper›PMID 40442398›Full record

ArticleScientific reports2025

In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents.

Aviral Shah, Kathan Desai, Ajaykumar Bhanusali, Shikha Agrawal, Khushbu Patel, Nilesh Naik, Anuj Thakar, Hem Naik, Dilip Kanjariya, Naved Malek and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Aviral ShahChemistry Department, Bhagwan Mahavir University, Vesu, Surat, 395007, Gujarat, India.
Kathan DesaiChemistry Department, Bhagwan Mahavir University, Vesu, Surat, 395007, Gujarat, India.
Ajaykumar BhanusaliChemistry Department, Bhagwan Mahavir University, Vesu, Surat, 395007, Gujarat, India.
Shikha AgrawalChemistry Department, Bhagwan Mahavir University, Vesu, Surat, 395007, Gujarat, India.
Khushbu PatelChemistry Department, Bhagwan Mahavir University, Vesu, Surat, 395007, Gujarat, India.
Nilesh NaikAnupam Rasayan India Limited, GIDC, Sachin, Surat, 8110, 394230, Gujarat, India.
Anuj ThakarAnupam Rasayan India Limited, GIDC, Sachin, Surat, 8110, 394230, Gujarat, India.
Hem NaikDepartment of Chemistry, S.V. National Institute of Technology, Surat, 395007, Gujarat, India.
Dilip KanjariyaDepartment of Chemistry, S.V. National Institute of Technology, Surat, 395007, Gujarat, India.
Naved MalekDepartment of Chemistry, S.V. National Institute of Technology, Surat, 395007, Gujarat, India.
Smita JauhariDepartment of Chemistry, S.V. National Institute of Technology, Surat, 395007, Gujarat, India.
Yogesh KadamDepartment of Chemistry, School of Science and Technology, Vanita Vishram Women's University, 395001, Surat, Gujarat, India.
Bhavesh PatelDepartment of Chemistry, Sir P. T. Sarvajanik College of Science, MTB College Campus, Jawaharlal Nehru Marg, Opposite Chaupati, 395007, Athwalines, Surat, Gujarat, India.
Ankit B ShahChemistry Department, Bhagwan Mahavir University, Vesu, Surat, 395007, Gujarat, India. shahankit1610@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel diphenylamine fluorinated chalcone derivatives (B1-B10) were synthesized and characterized using

Indexed as

AntimalarialsAntineoplastic AgentsChalconesDiphenylamineHalogenationHeLa CellsHumansMolecular Docking SimulationMolecular Dynamics SimulationPlasmodium falciparumAntimalarialsAntineoplastic AgentsChalconesDiphenylamineFluorinated diphenylamine ChalconesIn Silico studyIn vitro biological evaluationMethoxy functional group (-OCH3)

Identifiers

PMID40442398
PMCPMC12122917

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.