Evidence map›Paper›PMID 40442393›Full record

ArticleScientific reports2025

Long-term water immersion of dental composites based on bioactive glass.

Petra Gajski, Matej Par, Håvard J Haugen, Torben Hildebrand, Kai Zheng, Aldo R Boccaccini, Zrinka Tarle, Danijela Marovic

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Petra GajskiUniversity of Zagreb School of Dental Medicine, Zagreb, Croatia.
Matej ParDepartment of Endodontics and Restorative Dentistry, University of Zagreb School of Dental Medicine, Zagreb, Croatia.
Håvard J HaugenDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway. h.j.haugen@odont.uio.no.
Torben HildebrandDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.
Kai ZhengEngineering Research Centre of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.
Aldo R BoccacciniDepartment of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany.
Zrinka TarleDepartment of Endodontics and Restorative Dentistry, University of Zagreb School of Dental Medicine, Zagreb, Croatia.
Danijela MarovicDepartment of Endodontics and Restorative Dentistry, University of Zagreb School of Dental Medicine, Zagreb, Croatia. marovic@sfzg.unizg.hr.

Funding

Hrvatska Zaklada za Znanost IP-2024-05-2884
6 · The paper itself

Abstract

This study investigated the effect of copper-doped mesoporous bioactive glass nanospheres (Cu-MBGN) on water sorption, solubility and porosity of an experimental dental composite over 180 days of water immersion, comparing it to bioactive glass 45S5 (BG) or inert fillers. Composites contained 35wt% Bis-GMA/TEGDMA resin (60/40), 55wt% silanised barium-glass fillers, and 10wt% of either Cu-MBGN (10-CuBG), 45S5 bioactive glass (10-BG), or inert silica nanofillers (10-Si). Both BG composites showed a higher mass increase during water immersion than inert control (10-Si) at all measured time points (p < 0.001), ranked as 10-BG > 10-CuBG > 10-Si. After 30 days, 10-BG had the greatest mass increase (4.02 ± 0.21%), followed by a decline until 180 days, while 10-CuBG (1.67 ± 0.10%) and 10-Si (1.19 ± 0.07%) showed gradual mass increases until the end of the measurement. 10-BG displayed higher water sorption and solubility than other materials, while 10-CuBG had the highest porosity parameters. While 10-BG and 10-Si showed significant increases in both total and open porosity after water immersion, no such changes were observed for 10-CuBG. The pore characteristics of dry specimens did not affect final water sorption and solubility after 180 days of water immersion. The Cu-MBGN composite had a lower mass increase than commercial BG and met ISO 4049 standards for both water sorption and solubility.

Indexed as

Composite ResinsDental MaterialsGlassWaterCeramicsCopperImmersionMaterials TestingNanospheresPorositySilicon DioxideSolubilitybioactive glass 45S5Composite ResinsCopperDental MaterialsSilicon DioxideWaterBioactive glassDental materialsExperimental resin compositesPorositySolubilityWater sorption

Identifiers

PMID40442393
PMCPMC12122848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.