Evidence map›Paper›PMID 40442149›Full record

Trial reportScientific reports2025

The application of computerized quadrato motor training in enhancing balance and executive performance in stroke patients.

Cunshu Wu, YunYang, Wenjie Jin, Rong Cao, Jun Lu, Kailin Qian, Guangxu Xu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cunshu Wu *College of Rehabilitation Medicine, Nanjing Medical University, No.140 Hanzhong Road, Nanjing, 210029, Jiangsu, China.
YunYang *Rehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Wenjie Jin *College of Rehabilitation Medicine, Nanjing Medical University, No.140 Hanzhong Road, Nanjing, 210029, Jiangsu, China.
Rong CaoRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Jun LuRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
Kailin QianRehabilitation Medicine Center, Qixia Branch of the First Affiliated Hospital of Nanjing Medical University, No.28 Yaojia Road, Nanjing, 210046, Jiangsu, China.
Guangxu XuRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, Jiangsu, China. xuguangxu1@126.com.

Funding

Medical Science and Technology Development Foundation, Nanjing Municipality Health Bureau 2019060002
6 · The paper itself

Abstract

This study investigated the effects of Computerized Quadrato Motor Training (CQMT) on balance and executive function in both single- and dual-task conditions for stroke patients. Patients (n = 60) were randomized to three groups: conventional training (CT), exercise training (ET), and interactive motor-cognitive training (IT). All participants underwent CT. Besides, the ET group undertook step training, and the IT group underwent CQMT for four weeks. The assessments comprised balance function, executive function, lower limb strength, as well as self-efficacy of balance control. Balance function was assessed via the Pro-Kin system and standardized scales (Berg Balance Scale [BBS], Tinetti Assessment [POMA]). Executive function was assessed by the Trail Making Test (TMT-A / B) and Stroop test. Dual-task cost (DTC) derived from Timed Up-and-Go Test with/without cognitive loading (TUGT / TUGTcog). Balance self-efficacy was assessed by the Activities-specific Balance Confidence (ABC) Scale, with lower limb strength assessed by Five-Times Sit-to-Stand (FTSTS). After the intervention, the ET significantly showed improvement in the elliptical trajectory area, BBS, and gait performance compared to CT(P < 0.05). The IT group demonstrated significantly greater improvements in balance parameters (swing speed, elliptical trajectory area, trajectory lengths; P < 0.05) and functional outcomes (BBS, POMA, FTSTS, Dual-Task performance, TMT, Stroop, ABC; P < 0.01) compared to both CT and ET. The IT group showed significant positive correlations between TMT improvements and enhanced Dual-ask performance. Our findings demonstrate that CQMT, as an integrative motor-cognitive intervention, significantly improves balance and executive function in stroke patients, thereby filling a critical gap in the clinical application of QMT in stroke rehabilitation research. These findings validate the 'guided plasticity facilitation' theory, highlighting CQMT as a cost-effective and broadly applicable clinical training.Trial registration: The clinical trial was registered on 08/10/2023, with the registration number ChiCTR2300076424.

Indexed as

Executive FunctionExercise TherapyPostural BalanceStrokeStroke RehabilitationAgedFemaleHumansMaleMiddle AgedBalanceDual-taskExecutiveInteractive motor-cognitive trainingQuadrato motor trainingStroke

Identifiers

PMID40442149
PMCPMC12123033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.