Evidence map›Paper›PMID 40441695›Full record

ArticleACS chemical neuroscience2025

Prediction of Specificity of α-Conotoxins to Subtypes of Human Nicotinic Acetylcholine Receptors with Semi-supervised Machine Learning.

Hung Nguyen Do, Jessica Z Kubicek-Sutherland, Sandrasegaram Gnanakaran

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hung Nguyen DoTheoretical Biology and Biophysics Group, Theoretical Division, Los Alamos, New Mexico 87545, United States.ORCID 0000-0002-6497-4096
Jessica Z Kubicek-SutherlandPhysical Chemistry and Applied Spectroscopy Group, Chemistry Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, United States.ORCID 0000-0001-6215-4871
Sandrasegaram GnanakaranTheoretical Biology and Biophysics Group, Theoretical Division, Los Alamos, New Mexico 87545, United States.ORCID 0000-0002-9368-3044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conotoxins are a family of highly toxic neurotoxins composed of cysteine-rich peptides produced by marine cone snails. The most lethal cone snail species to humans is

Indexed as

ConotoxinsMachine LearningReceptors, NicotinicSupervised Machine LearningAmino Acid SequenceConus SnailHumansProtein BindingConotoxinsReceptors, Nicotinicdeep neural networksnicotinic acetylcholine receptorssemi-supervised machine learningtoxin specificityα-conotoxins

Identifiers

PMID40441695
PMCPMC12183688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.