Evidence map›Paper›PMID 40440878›Full record

ArticleThe Journal of surgical research2025

Hernia Recurrence Risk Matters More Than Mesh Type to Patients Undergoing Ventral Hernia Repair.

Stephanie Martinez Ugarte, Mokunfayo O Fajemisin, Chelsea J Guy-Frank, Dalya M Ferguson, Jonah J Stulberg, Lillian S Kao, Julie L Holihan

Abstract read
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In one paragraph

Article in The Journal of surgical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie Martinez UgarteDepartment of Surgery, Center for Translational Injury Research, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Division of Acute Care Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Center for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Mokunfayo O FajemisinDepartment of Surgery, Center for Translational Injury Research, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Division of Acute Care Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Center for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Chelsea J Guy-FrankDivision of Acute Care Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Center for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Dalya M FergusonCenter for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Division of Elective General Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Jonah J StulbergCenter for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Division of Elective General Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Lillian S KaoDivision of Acute Care Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Center for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Julie L HolihanCenter for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas; Division of Elective General Surgery, Department of Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas. Electronic address: julie.l.holihan@uth.tmc.edu.

Funding

ROLE OF THE GUT IN POST INJURY MULTIPLE ORGAN FAILURET32GM008792 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Charles S Cox · 2001 to 2026
$5.2M
Institutional Career Development CoreKL2TR003168 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, CHARLES C · 2019 to 2023
$4.9M
NCATS NIH HHS KL2 TR003168NIGMS NIH HHS T32 GM008792
6 · The paper itself

Abstract

introductionPatients' perceptions about synthetic mesh for ventral hernia repair (VHR) may stem from a lack of knowledge of risks. We assessed patients' threshold for accepting the risk of hernia recurrence to avoid synthetic mesh.

methodsPatients ≥18 y old with prior or upcoming VHR viewed a one-time video decision aid describing recurrence risk with biologic versus synthetic mesh. Patients chose between these options using a probability trade-off (PTO) technique, varying hernia recurrence rate with biologic mesh. Based on randomized trials, the recurrence rate using synthetic mesh was 9%. The PTO score was the recurrence rate (0%-100%) at which patients would no longer choose biologic mesh. The process was repeated, including expected wound complications with each mesh. Linear regression identified factors associated with higher PTO scores (risk aversion to synthetic mesh).

resultsOf 100 patients, 57% always preferred synthetic mesh, 3% accepted a higher recurrence risk to have synthetic mesh, and 24% preferred biologic mesh but only if the recurrence rate was lower than with synthetic mesh. In addition, 15% accepted a higher recurrence risk to have biologic mesh, and 1% always preferred biologic mesh despite a higher hernia recurrence rate. Information on wound complications had little impact on mesh choice. On multivariable analysis, higher education and postoperative interviews were associated with higher PTO thresholds.

conclusionsContrary to the common belief that patients prefer to avoid synthetic mesh, this study showed that most patients prioritized reducing hernia recurrence risk over mesh type. Further studies should identify patient's goals and priorities for outcomes following VHR.

Indexed as

Hernia, VentralHerniorrhaphyPatient PreferenceSurgical MeshAdultAgedDecision Support TechniquesFemaleHumansMaleMiddle AgedRecurrenceBiologic meshMeshPatient-centered outcomesPermanent meshProbability trade-offSynthetic meshVentral hernia

Identifiers

PMID40440878
PMCPMC12356600

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.