Evidence map›Paper›PMID 40440515›Full record

ArticleMedicine and science in sports and exercise2025

An Exercise Intervention May Counteract the Degradation of Nerve Conduction from Age-Related Disuse.

Jocarol E Shields, Claire M Smith, Shawn M Reese, Marcel L Dos Santos, Maria Parodi, Jason M Defreitas

Abstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jocarol E ShieldsNeural Health Research Laboratory, Falk College, Syracuse University, Syracuse, NY.
Claire M SmithNeural Health Research Laboratory, Falk College, Syracuse University, Syracuse, NY.
Shawn M ReeseDepartment of Health and Human Performance, Fairmont State University, Fairmont, WV.
Marcel L Dos SantosSchool of Kinesiology and Recreation, Illinois State University, Normal, IL.
Maria ParodiApplied Neuromuscular Physiology Laboratory, Oklahoma State University, Stillwater, OK.
Jason M DefreitasNeural Health Research Laboratory, Falk College, Syracuse University, Syracuse, NY.ORCID 0000-0002-5108-8079

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
NIGMS NIH HHS P20 GM103434
6 · The paper itself

Abstract

purposeThe purpose was twofold: first, to determine the effects of resistance training on nerve conduction velocity (NCV), and second, to determine if changes in NCV are dependent on age. We hypothesized that training would result in faster nerve conduction in both young and older adults, albeit to a lesser extent in older adults.

methodsForty-eight subjects (18-84 yr) completed this study (training: n = 14 younger, 14 older; control: n = 12 younger, 8 older). Median motor NCV and maximal strength were recorded before and after 4 wk of handgrip training in both limbs. Training was conducted 3×/wk with the use of a grip training kit.

resultsMixed-factorial ANOVA revealed significant increases in NCV for both the young ( P < 0.001, Cohen's d = 0.749) and older training groups ( P < 0.001, Cohen's d = 0.679), but neither in control groups (young: P = 0.353, Cohen's d = 0.326; older: P = 0.108, Cohen's d = -0.184).

conclusionsThe results of this study suggest that resistance training may be a viable method to counteract age-related nerve deterioration. These outcomes have the potential to improve quality of life and generate greater independence for our older populations.

Indexed as

AgingNeural ConductionResistance TrainingAdolescentAdultAgedAged, 80 and overAge FactorsFemaleHand StrengthHumansMaleMiddle AgedYoung AdultAGINGMOTOR NERVE CONDUCTION VELOCITYNERVE DETERORIATIONRESISTANCE TRAINING

Identifiers

PMID40440515
PMCPMC13007915

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.