Evidence map›Paper›PMID 40440425›Full record

Observational studyPloS one2025

Impact of functional status and biomarkers on hospital costs and readmission rates in geriatric patients: An observational study with comprehensive geriatric assessment.

Irene Simonetti, Stefano Landi, Chiara Leardini, Anna Giani, Arianna Bortolani, Francesco Fantin

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Irene SimonettiEconomics and Business, University of Amsterdam, The Netherlands.ORCID 0000-0001-6200-2018
Stefano LandiDepartment of Management, University of Verona, Verona, Italy.
Chiara LeardiniDepartment of Management, University of Verona, Verona, Italy.
Anna GianiSection of Geriatric Medicine, Department of Medicine, University of Verona, Verona, Italy.
Arianna BortolaniSection of Geriatric Medicine, Department of Medicine, University of Verona, Verona, Italy.
Francesco FantinSection of Geriatric Medicine, Department of Medicine, University of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to analyze the association between functional status, biomarkers, and hospitalization characteristics on costs and the probability of re-admission at 30 and 180 days in geriatric patients. It is used an observational design with both administrative data and additional clinical data not usually collected. Multivariate linear regression for hospitalization costs and multivariate logistic regressions for readmissions were used. Variables studied included the Barthel Index, Charlson index, albumin and blood pressure levels, previous hospitalizations, length of stay (LoS), and controls. Data from 953 patients aged over 65, admitted to the Geriatric ward between September 1st, 2018, and December 31st, 2019, were analyzed. The Charlson comorbidity index, number of comorbidities, and LoS were positively related to hospitalization costs. Previous hospitalizations and LoS were the main predictors of readmission. Systolic blood pressure was negatively associated with the odds of re-admission but showed no association with hospital costs. Higher functional status, as measured by the Barthel index, was linked to lower odds of unplanned hospitalization but was not statistically significant for costs. Functional status and biomarkers had moderate effects on costs and readmission odds. These findings can aid in early healthcare planning and resource management, providing valuable information for prioritizing patients and designing cost-effective care interventions.

Indexed as

BiomarkersFunctional StatusGeriatric AssessmentHospital CostsPatient ReadmissionAgedAged, 80 and overComorbidityFemaleHospitalizationHumansLength of StayMaleBiomarkers

Identifiers

PMID40440425
PMCPMC12121913

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.