Evidence map›Paper›PMID 40440366›Full record

ArticleScience (New York, N.Y.)2025

Enamel proteins reveal biological sex and genetic variability in southern African

Palesa P Madupe, Claire Koenig, Ioannis Patramanis, Patrick L Rüther, Nomawethu Hlazo, Meaghan Mackie, Mirriam Tawane, Johanna Krueger, Alberto J Taurozzi, Gaudry Troché and 28 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Palesa P Madupe *Globe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0001-5514-5221
Claire Koenig *Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0002-7327-2723
Ioannis Patramanis *Globe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0002-1852-2451
Patrick L RütherNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0003-4461-9828
Nomawethu HlazoHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-5495-1790
Meaghan MackieGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0003-0763-7592
Mirriam TawaneHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-5265-7846
Johanna KruegerInstitute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain.ORCID 0000-0002-2685-718X
Alberto J TaurozziGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0003-0378-1626
Gaudry TrochéGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0002-0404-4030
Job KibiiTurkana Basin Institute, Nairobi, Kenya.ORCID 0000-0003-4113-0592
Robyn PickeringHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-2663-7574
Marc R DickinsonDepartment of Chemistry, University of York, York, UK.ORCID 0000-0003-0465-1612
Yonatan SahleHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-1098-1685
Dipuo KgotlengPalaeo-Research Institute, University of Johannesburg, Johannesburg, South Africa.ORCID 0000-0003-2160-7090
Charles MusibaHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-4297-5178
Fredrick ManthiHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0009-0007-7973-9463
Liam BellD-CYPHR, Centre for Proteomic and Genomic Research, Cape Town, South Africa.ORCID 0000-0001-7791-7472
Michelle DuPlessisD-CYPHR, Centre for Proteomic and Genomic Research, Cape Town, South Africa.ORCID 0000-0002-7905-6845
Catherine GilbertCBMN UMR CNRS 5248, Bordeaux Proteome, University of Bordeaux, Bordeaux, France.ORCID 0000-0002-3382-7149
Bernhard ZipfelEvolutionary Studies Institute, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-4251-884X
Lukas F K KudernaInstitute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain.ORCID 0000-0002-9992-9295
Esther LizanoInstitut Català de Paleontologia Miquel Crusafont (ICP-CERCA), Universitat Autònoma de Barcelona, Edifici ICTA-ICP, Cerdanyola del Vallès, Spain.ORCID 0000-0003-3304-9807
Frido WelkerGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0002-4846-6104
Pelagia KyriakidouComputational Systems Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.ORCID 0000-0002-1139-715X
Jürgen CoxUnidad de Paleobiología, ICP-CERCA, Unidad Asociada al CSIC por el IBE UPF-CSIC, Cerdanyola del Vallès, Barcelona, Spain.ORCID 0000-0001-8597-205X
Catherine MollereauResearch Center on Animal Cognition (CRCA), University of Toulouse, Toulouse, France.ORCID 0000-0003-1543-5624
Caroline TokarskiCBMN UMR CNRS 5248, Bordeaux Proteome, University of Bordeaux, Bordeaux, France.ORCID 0000-0001-7296-3330
Jonathan BlackburnInstitute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-8988-9595
Jazmín Ramos-MadrigalGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0002-1661-7991
Tomas Marques-BonetInstitute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain.ORCID 0000-0002-5597-3075
Kirsty PenkmanDepartment of Chemistry, University of York, York, UK.ORCID 0000-0002-6226-9799
Clément ZanolliEvolutionary Studies Institute, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-5617-1613
Lauren SchroederHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-6406-8096
Fernando RacimoGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0002-5025-2607
Jesper V OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen N, Denmark.ORCID 0000-0002-4747-4938
Rebecca R AckermannHuman Evolution Research Institute (HERI), University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-8757-6878
Enrico CappelliniGlobe Institute, University of Copenhagen, Copenhagen K, Denmark.ORCID 0000-0001-7885-7811

Funding

European Research Council 101021361
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dental EnamelDental Enamel ProteinsFossilsGenetic VariationHominidaeSex CharacteristicsAnimalsFemaleMaleMass SpectrometryPaleodontologyProteomicsSouth AfricaDental Enamel Proteins

Identifiers

PMID40440366
PMCPMC7617798

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.