Evidence map›Paper›PMID 40440356›Full record

ArticleThe British journal of dermatology2025

Residential ambient ultraviolet B and ultraviolet A and incidence of keratinocyte carcinoma in the nationwide US Radiologic Technologists cohort.

Jim Z Mai, Cari M Kitahara, Michael R Sargen, Mark P Little, Bruce H Alexander, Martha S Linet, Elizabeth K Cahoon

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In one paragraph

Article in The British journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jim Z MaiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.ORCID 0000-0001-9772-0669
Cari M KitaharaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
Michael R SargenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
Mark P LittleDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
Bruce H AlexanderDivision of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Martha S LinetDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
Elizabeth K CahoonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.

Funding

Division of Cancer Epidemiology and Genetics, National Cancer InstituteHHS
6 · The paper itself

Abstract

backgroundFew epidemiological studies have distinguished the effects of solar ultraviolet (UV) radiation (UVR) wavelength, including UVB and UVA, on the risk of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin.

objectivesWe aimed to evaluate the association between ambient UVB and UVA exposure and the incidence of BCC and SCC.

methodsUsing data from the nationwide US Radiologic Technologists cohort, satellite-based noontime ambient UVR was obtained based on residential history (< 13, 13-19, 20-39, 40-64, and ≥ 65 years). Incidence rate ratios (IRRs) and 95% confidence intervals (CIs) were estimated for associations between UVB, UVA quintile (Q), and first primary BCC and SCC in mutually adjusted and stratified models, additionally adjusted for sun sensitivity characteristics.

resultsThere were 62 595 non-Hispanic White participants aged 22-90 years at baseline (1983-1998). During a median 25.5 years of follow-up, 6339 incident BCCs and 1253 incident SCCs were reported. Annual and summer UVB and UVA were each positively associated with both BCC and SCC risk before mutual adjustment. After adjusting for UVA, summer (but not annual) UVB Q5 vs. Q1 was associated with BCC (IRR 1.41, 95% CI 1.13-1.77) and SCC (IRR 1.69, 95% CI 1.01-2.84). After adjusting for UVB, annual (but not summer) UVA Q5 vs. Q1 was associated with BCC (IRR 1.42, 95% CI 1.13-1.77) and SCC (IRR 1.84, 95% CI 1.10-3.06).

conclusionsBoth summer UVB and annual UVA were independently associated with higher risks of both BCC and SCC. Our results suggest that cumulative lifetime UVA exposure may be an underappreciated contributor to BCC and SCC risk. If confirmed, these findings may indicate that public health interventions are required to promote avoidance of excessive UVB and UVA exposure among susceptible populations.

Indexed as

Basal Cell CarcinomaCarcinoma, Squamous CellNeoplasms, Radiation-InducedSkin NeoplasmsUltraviolet RaysAdultAgedAged, 80 and overCohort StudiesFemaleHumansIncidenceKeratinocytesMaleMiddle AgedSeasons

Identifiers

PMID40440356
PMCPMC13338620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.