Evidence map›Paper›PMID 40440291›Full record

ArticlePLOS global public health2025

Neurodevelopmental delay and associated factors among preterm infants aged 6 to 24 months adjusted gestation age in two urban hospitals in Uganda.

Joyce Nalwoga, Victoria Nakibuuka, Leonard Manirakiza, Tracy Tushabe Namata, Robert Sebunya

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Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Joyce NalwogaDepartment of Pediatrics, St Francis Nsambya Hospital, Kampala, Uganda.
Victoria NakibuukaDepartment of Pediatrics, St Francis Nsambya Hospital, Kampala, Uganda.
Leonard ManirakizaUganda National Bureau of Standards, Kampala, Uganda.ORCID https://orcid.org/0000-0001-7273-2866
Tracy Tushabe NamataDepartment of Pediatrics, St Francis Nsambya Hospital, Kampala, Uganda.ORCID https://orcid.org/0009-0002-8393-9437
Robert SebunyaDepartment of Pediatrics, St Francis Nsambya Hospital, Kampala, Uganda.ORCID https://orcid.org/0000-0001-7666-3298

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodevelopmental delay has been reported among preterm infants who survive beyond the neonatal period. However, there is paucity of data regarding neurodevelopmental outcomes in preterm infants in Africa, including Uganda. This study aimed to determine the prevalence and factors associated with neurodevelopment delay (NDD) in preterm infants aged 6-24 months of adjusted gestation age. A cross-sectional study was conducted among 206 preterm infants, aged between 6 and 24 months of adjusted gestation age in the preterm follow up clinics at St. Francis Hospital Nsambya and Mulago Specialized Women and Neonatal Hospital in Kampala-Uganda from 25th January 2021-25th January 2022. The prevalence of NDD was 13.6% (28/206), with social delay comprising 12.1% (25/206), fine motor delay 11.7% (24/206), language delay 10.7% (22/206) and gross motor delay 7.8% (16/206). Significant factors associated with NDD included microcephaly [aPR = 6.2, CI: 2.6-33.5, P < 0.001], severe acute malnutrition (SAM) [aPR = 4.6, CI: 1.87-12.56, P = 0.021], incomplete immunization [aPR = 2.8, CI: 1.23-4.76, P = 0.013], neonatal sepsis [aPR = 3.8, CI: 1.1-9.3, P = 0.026], neonatal hypoglycemia [aPR = 6.2, CI: 1.8-16.4, P = 0.002], lack of caretaker social support [aPR = 8.3, CI: 2.43-37.9, P = 0.002] and large family size (≥5 children) [aPR = 6.8, CI: 2.24-22.7, P = 0.002]. NDD affects 13.6% of preterm infants, with the social and fine motor delays being most prevalent. Modifiable factors like malnutrition, lack of caretaker social support and incomplete immunization should be screened and addressed to reduce NDD among preterm infants in Uganda.

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PMID40440291
PMCPMC12121762

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