Evidence map›Paper›PMID 40440068›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Histone variant H2A.W7 represses meiotic crossover formation in

Pallas Kuo, Andrew J Tock, Xuexia Liu, Stephanie D Topp, Zhenhui Zhong, Ian R Henderson, Christophe Lambing

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pallas KuoDepartment of Plant Sciences, Rothamsted Research, Harpenden AL5 2JQ, United Kingdom.
Andrew J TockDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.ORCID 0000-0002-6590-8314
Xuexia LiuMinistry of Education Key Laboratory for Bio-Resource and Eco-Environment, College of Life Sciences, State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu 610064, China.
Stephanie D ToppDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Zhenhui ZhongMinistry of Education Key Laboratory for Bio-Resource and Eco-Environment, College of Life Sciences, State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu 610064, China.ORCID 0000-0002-8438-0375
Ian R HendersonDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.ORCID 0000-0001-5066-1489
Christophe LambingDepartment of Plant Sciences, Rothamsted Research, Harpenden AL5 2JQ, United Kingdom.ORCID 0009-0009-6218-3889

Funding

EC | European Research Council (ERC) ERC-2015-CoG-681987UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Y001591/1
6 · The paper itself

Abstract

In eukaryotic genomes, DNA is packaged into nucleosomes to form chromatin. The incorporation of canonical or variant histones into nucleosomes confers different properties and influences chromatin structure to regulate cellular processes, including recombination. During meiosis, DNA double-strand breaks (DSBs) are formed and repaired as interhomolog crossovers. Nucleosome occupancy is generally associated with low crossover frequency, but it remains unclear which histone variants are involved in this process. In

Indexed as

ArabidopsisArabidopsis ProteinsCrossing Over, GeneticHeterochromatinHistonesMeiosisDNA Breaks, Double-StrandedDNA MethylationNucleosomesArabidopsis ProteinsHeterochromatinHistonesNucleosomescrossoverepigeneticsH2A.Wmeiosisnucleosomes

Identifiers

PMID40440068
PMCPMC12146724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.