Evidence map›Paper›PMID 40440032›Full record

ReviewBiochemical Society transactions2025

Mechanisms of heme transport in the mitochondria.

Saieeda Fabia Ali, Adrianna E White, Amy Medlock, Oleh Khalimonchuk

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saieeda Fabia AliDepartment of Biochemistry, University of Nebraska-Lincoln, Lincoln NE 68588U.S.A.
Adrianna E WhiteDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens GA 30602U.S.A.
Amy MedlockDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens GA 30602U.S.A.
Oleh KhalimonchukDepartment of Biochemistry, University of Nebraska-Lincoln, Lincoln NE 68588U.S.A.ORCID 0000-0002-3972-8678

Funding

Mitochondrial Fidelity and HomeostasisR35GM131701 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI Oleh Khalimonchuk · 2019 to 2026
$2.4M
NIGMS NIH HHS R35 GM131701
6 · The paper itself

Abstract

Heme is a vital but highly reactive compound that is synthesized in mitochondria and subsequently distributed to a variety of subcellular compartments for utilization. The transport of heme is essential for normal cellular metabolism, growth, and development. Despite the vital importance of heme transport within the cell, data are lacking about how newly synthesized heme is shuttled within the mitochondrion or exported from the organelle. Here, we briefly summarize current knowledge about the process of mitochondrial heme distribution and discuss the current unresolved questions pertinent to this process.

Indexed as

HemeMitochondriaAnimalsBiological TransportHumansHemehemeheme biosynthesishemoproteinsmembrane transportersmitochondria

Identifiers

PMID40440032
PMCPMC12224909

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.