Evidence map›Paper›PMID 40439964›Full record

ArticleObesity surgery2025

Impact of Sleeve Gastrectomy on Ectopic Fat Deposition and Skeletal Muscle Composition Across Glucose Metabolic States.

Xiang Gao, Junhong Duan, Beibei Cui, Pengzhou Li, Zhihong Su, Weizheng Li, Zhi Song, Shaihong Zhu, Pengfei Rong, Liyong Zhu

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In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiang GaoCentral South University, Changsha, China.
Junhong DuanCentral South University, Changsha, China.
Beibei CuiCentral South University, Changsha, China.
Pengzhou LiCentral South University, Changsha, China.
Zhihong SuCentral South University, Changsha, China.
Weizheng LiCentral South University, Changsha, China.
Zhi SongCentral South University, Changsha, China.
Shaihong ZhuCentral South University, Changsha, China.
Pengfei RongCentral South University, Changsha, China.
Liyong ZhuCentral South University, Changsha, China. zly8128@csu.edu.cn.

Funding

National Natural Science Foundation of China 82370676
6 · The paper itself

Abstract

backgroundDifferences in abdominal fat and muscle composition among patients with obesity across glycemic statuses-and the modulatory role of metabolic bariatric surgery (MBS) on these interrelationships-remain unclear. This study thus aims to elucidate the interplay between body composition and glycemic status, and to assess how MBS differentially impacts metabolic parameters and body composition outcomes in these patient groups.

methodsIn this single-center prospective study, 49 patients with obesity (31 with impaired glucose metabolism [IGM], 18 with normal glucose tolerance [NGT]) underwent Dixon MRI for fat/water separation to assess pancreatic, hepatic, and muscle fat. Measurements were taken preoperatively and 3 months post-laparoscopic sleeve gastrectomy.

resultsThe study included 18 patients with NGT (2 male/16 female; mean age 26.22 ± 7.17 years) and 31 with IGM (16 male/15 female; mean age 33.52 ± 10.65years). Both groups showed significant postoperative reductions in all measured parameters (P < 0.0001). The IGM group demonstrated greater decreases in visceral fat (88.33 ± 38.33 vs. 54.68 ± 25.91 cm

conclusionsPatients with obesity and IGM have higher visceral fat, pancreatic fat, and erector spinae mass than their NGT counterparts. Following bariatric surgery, they experience greater reductions in liver fat, pancreatic fat, and muscle areas. These findings suggest differential metabolic effects based on preoperative glucose status. However, further large-scale studies are needed to confirm.

Indexed as

Blood GlucoseGastrectomyGlucose IntoleranceMuscle, SkeletalObesity, MorbidAdultBody CompositionFemaleHumansIntra-Abdominal FatLaparoscopyMagnetic Resonance ImagingMaleProspective StudiesTreatment OutcomeWeight LossBlood GlucoseEctopic fatGlucose metabolismLaparoscopic sleeve gastrectomyMuscleObesity

Identifiers

PMID40439964

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.