Evidence map›Paper›PMID 40439941›Full record

ArticleSurgery today2025

Risk factors for anastomotic leakage and long-term outcomes after laparoscopic right colectomy: a multicenter study in a Japanese rural area.

Rika Ono, Tetsuro Tominaga, Takashi Nonaka, Yuma Takamura, Kaido Oishi, Shintaro Hashimoto, Toshio Shiraishi, Keisuke Noda, Makoto Hisanaga, Akiko Fukuda and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rika OnoDepartment of Surgery, Sasebo City General Hospital, 9-3 Hirasemachi, Nagasaki, 857-8511, Japan.
Tetsuro TominagaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. tetsuro.tominaga@nagasaki-u.ac.jp.
Takashi NonakaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Yuma TakamuraDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Kaido OishiDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Shintaro HashimotoDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Toshio ShiraishiDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Keisuke NodaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Makoto HisanagaDepartment of Surgery, Sasebo City General Hospital, 9-3 Hirasemachi, Nagasaki, 857-8511, Japan.
Akiko FukudaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, 1-1001-1, Omura, Nagasaki, 856-8562, Japan.
Masaaki MoriyamaDepartment of Surgery, Isahaya General Hospital, 24-1, Isahaya , Nagasaki, 854-8501, Japan.
Keizaburo MaruyamaDepartment of Surgery, Ureshino Medical Center, 4279-3 Ko, Ureshinomachi, Oaza, Shimojuku, Ureshino, Saga, 843-0393, Japan.
Shoko TeiDepartment of Surgery, Ureshino Medical Center, 4279-3 Ko, Ureshinomachi, Oaza, Shimojuku, Ureshino, Saga, 843-0393, Japan.
Kazuhide IshimaruDepartment of Surgery, Saiseikai Nagasaki Hospital, 2-5-1 Katafuchi, Nagasaki, 850-0003, Japan.
Keitaro MatsumotoDepartment of Surgery, Sasebo City General Hospital, 9-3 Hirasemachi, Nagasaki, 857-8511, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study used a Japanese multicenter database to identify risk factors for anastomotic leakage (AL) and evaluate the long-term outcomes of patients who underwent laparoscopic right colectomy.

methodsThe subjects of this retrospective review were 729 patients who underwent laparoscopic right colectomy. Clinical features were compared between patients who suffered AL (n = 33) and those who did not (n = 696).

resultsMultivariate analysis identified pulmonary disease (odds ratio [OR] 6.681, 95% confidence interval [CI] 1.495-19.864; p = 0.012), steroid use (OR 10.930, 95%CI 6.131-14.783; p < 0.001), open conversion (OR 12.648, 95%CI 5.479-15.438; p < 0.001), and blood loss ≥ 25 ml (OR 3.260, 95%CI 1.407-7.553; p = 0.005) as independent prognostic factors for AL. The five-year recurrence-free survival (RFS) rates were 43.6% in the AL group and 80.3% in the non-AL group (p = 0.016), while the 5-year overall survival (OS) rates were 71.3% in the AL group and 85.8% in the non-AL group (p = 0.027). Multivariate analysis identified AL (HR 1.519, 95%CI 1.646-3.591; p = 0.037) as the only independent predictor of OS.

conclusionsPulmonary disease, steroid use, and open conversion were identified as risk factors for AL in patients who underwent laparoscopic right colectomy. AL was associated with poor prognosis. Achievement of good short- and long-term results will require careful perioperative management of patients with these risk factors.

Indexed as

Anastomotic LeakColectomyLaparoscopyAdultAgedAged, 80 and overBlood Loss, SurgicalFemaleHumansJapanLung DiseasesMaleMiddle AgedMultivariate AnalysisPrognosisRetrospective StudiesSteroidsAnastomotic leakageMortalityRight colon cancer

Identifiers

PMID40439941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.