Evidence map›Paper›PMID 40439926›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Endoscopic ossiculoplasty: audiological and surgical outcomes from a multicenter experience with 292 cases.

Raffael Fink, Giulia Molinari, Arianna Burato, Daniel Stricker, Nicola Bisi, Daniele Marchioni, Livio Presutti, Ignacio Javier Fernandez, Lukas Anschuetz

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raffael FinkDepartment of Otorhinolaryngology, Head and Neck Surgery, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland. Raffaeldfink@gmail.com.ORCID http://orcid.org/0009-0007-6396-7867
Giulia MolinariDepartment of Otolaryngology, Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Arianna BuratoDepartment of Otolaryngology, Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Daniel StrickerInstitute of Medical Education, University of Bern, Bern, Switzerland.
Nicola BisiDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Modena, Modena, Italy.
Daniele MarchioniDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Modena, Modena, Italy.
Livio PresuttiDepartment of Otolaryngology, Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Ignacio Javier FernandezAlma Mater Studiorum-Università di Bologna, Bologna, Italy.
Lukas AnschuetzDepartment of Otorhinolaryngology, Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate surgical and audiological outcomes of different endoscopic ossiculoplasty (endo-OPL) techniques and prosthesis materials.

methodsIn this multicenter retrospective study, 292 patients underwent endo-OPL for various ossicular chain pathologies at three university hospitals between 2017 and 2023. We analyzed pre- and postoperative hearing metrics, perforation characteristics, surgical procedures, prosthesis types, and complication rates.

resultsThe cohort showed significant audiological improvement, with the mean preoperative air-bone gap (ABG) reducing from 26.88 dB (SD ± 12.73) to 19.94 dB (SD ± 10.90) at the last follow-up (FU; mean 20.7 months ± 15.53) (p = 0.001), and a graft success rate of 94.2%. Significant postoperative ABG improvements were observed with bony partial ossicular replacement prostheses (PORP) (p < 0.001), titanium total ossicular replacement prostheses (TORP) (p = 0.008), and semi-synthetic TORP (p = 0.016). Both cement PORP and bony PORP groups showed consistent ABG improvements over two FU visits. Conversely, titanium based PORP and TORP demonstrated initial improvements but later showed deterioration. Prosthesis extrusion and dislocation rates were 8.4% and 4.2% for titanium PORP, and 0% and 5.2% for titanium TORP, respectively, at the last FU. Endo-OPL combined with additional mastoidectomy (n = 59) did not yield significant ABG improvements.

conclusionThis multicenter study supports the efficacy of endo-OPL as a valuable technique to improve hearing outcomes in patients with conductive or mixed hearing loss. It highlights the superior performance of specific prosthesis materials and demonstrates that endo-OPL without additional mastoidectomy provides better hearing results, emphasizing the benefits of mastoid preservation in exclusive endoscopic procedures.

Indexed as

EndoscopyHearing Loss, ConductiveOssicular ProsthesisOssicular ReplacementAdolescentAdultAgedBone ConductionChildEar OssiclesFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAir-bone gapAudiological outcomesEar surgeryEndoscopic ossiculoplastyMastoid preservationOssicular replacement prostheses

Identifiers

PMID40439926
PMCPMC12605371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.