Evidence map›Paper›PMID 40439870›Full record

Observational studySports medicine (Auckland, N.Z.)2025

Long-Term Knee Health in Adults with a History of Adolescent Osgood-Schlatter: A National Cohort Study of Patients in Secondary Care in Denmark 1977-2020.

Kasper Krommes, Amalie Bjerre, Kristian Thorborg, Mathias Fabricius Nielsen, Per Hölmich

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Sports medicine (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04313621 (Management of Lower Limb Apophysitis), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04313621 completednot on this map

Management of Lower Limb Apophysitis: A Cross-sectional Study on Long-term Impact on Health Status

Typeobservational_patient_registrySponsorHvidovre University HospitalRan2021 to 2021Enrolled1,218ConditionsLower Limb Apophysitis (Severs, Osgood Schlatter, Sinding-Larsen Johansson)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Non-surgical treatment for lower limb apophyseal injuries.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kasper KrommesSports Orthopedic Research Center-Copenhagen, Orthopedic Department, Amager-Hvidovre, Copenhagen University Hospital, Copenhagen, Denmark. kasper.krommes@regionh.dk.
Amalie BjerreSports Orthopedic Research Center-Copenhagen, Orthopedic Department, Amager-Hvidovre, Copenhagen University Hospital, Copenhagen, Denmark.
Kristian ThorborgSports Orthopedic Research Center-Copenhagen, Orthopedic Department, Amager-Hvidovre, Copenhagen University Hospital, Copenhagen, Denmark.
Mathias Fabricius NielsenSports Orthopedic Research Center-Copenhagen, Orthopedic Department, Amager-Hvidovre, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0003-4211-3516
Per HölmichSports Orthopedic Research Center-Copenhagen, Orthopedic Department, Amager-Hvidovre, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0003-2098-0272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsgood-Schlatter has, until recently, been suggested to be a benign condition, affecting adolescents in terms of knee pain and decreased sports participation during growth, with no long-term consequences seen later in adulthood.

objectivesThe objectives of this study were to describe the long-term knee health in adults with a history of Osgood-Schlatter, compare these findings with healthy population estimates, and investigate if explanatory variables are associated with current knee health.

methodsThe Danish Patient Registry identified patients ≥ 18 years diagnosed with adolescent Osgood-Schlatter in hospitals during 1977-2020. All cases participated in a survey about knee-related health and comorbidities. Existing literature was sourced for the healthy population estimates for comparisons. Explanatory variables were recalled Osgood-Schlatter duration, pain levels, restrictions, and current tibial tubercle prominence.

resultsOf 1281 identified patients, 400 responded. Most reported having a current bony prominence of the tibial tubercle (85%) and sustained pain/problems from the same area (73%). Compared with healthy population estimates, Osgood-Schlatter cases scored lower on the Knee Injury and Osteoarthritis Outcome Score on all subscales (p < 0.05), particularly for "sport/rec" and "quality of life" (Cohen's d > 0.8). Similarly, cases exhibited a large risk of "jumper's knee" (odds ratio: 70.4 [95% confidence intervals, CI: 32.9; 155.0], p < 0.0001). Symptom duration and pain levels were negatively associated with several outcomes (p < 0.05).

conclusionsAdults with a history of Osgood-Schlatter have significantly worse long-term knee health than what is observed from healthy population estimates. Recalled longer symptom duration and higher pain levels were associated with worse current knee health. This information should potentially guide management to maintain knee health over time, as the condition is not always as benign and self-limiting as previously thought. REGISTRATION: NCT04313621.

Indexed as

Knee JointOsteochondrosisAdolescentAdultArthralgiaCohort StudiesDenmarkFemaleHumansKnee InjuriesMaleMiddle AgedRegistriesYoung Adult

Identifiers

PMID40439870
PMCPMC12296839

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.