Evidence map›Paper›PMID 40439760›Full record

ArticleAesthetic plastic surgery2026

A Biomechanical Analysis of Barbed and Monofilament Suture in an Ex Vivo Skin Closure Model.

Jacob G Mabey, Alexander J Kammien, Vikram G Mookerjee, J Grant Thomson

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacob G MabeyDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, Yale School of Medicine, PO Box 208041, New Haven, CT, USA.
Alexander J KammienDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar St, Suite BB330, New Haven, CT, USA.
Vikram G MookerjeeDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar St, Suite BB330, New Haven, CT, USA.
J Grant ThomsonDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar St, Suite BB330, New Haven, CT, USA. grant.thomson@yale.edu.ORCID 0000-0002-5995-5923

Funding

Medtronic ERP-2021-12721NIDDK NIH HHS 5T35DK104689-0
6 · The paper itself

Abstract

backgroundPrevious studies propose that barbed suture may have equivalent tensile strength and reduced suturing time compared to traditional suture materials, but this has not been tested in skin closure using tissue from living human donors.

methodsTwenty-four 5 cm by 2.5 cm samples were cut from twelve skin and subcutaneous tissue specimens that were obtained from abdominal wall procedures. Each sample was sectioned in half, and the skin was then closed using one of two techniques: knotless (running subcuticular with 3-0 barbed suture and skin glue) or layered closure (deep dermal sutures with 3-0 poliglecaprone, running subcuticular with 4-0 poliglecaprone and skin glue). Closure time and load to failure were recorded and compared using t-tests.

resultsMean closure time was significantly shorter for the knotless technique (2.2 ± 0.6 minutes) compared to layered closure (5.6 ± 0.5 minutes). Regarding tensile strength, mean load to failure for the knotless closure (46.5 ± 22.2 N) was significantly lower than the layered closure (79.3 ± 39.1 N). All techniques failed due to suture rupture.

conclusionsKnotless closures significantly reduced closure time but were weaker than layered closures. All closures exceeded estimates of clinical tension in wound closure, suggesting that knotless skin closures may be a viable option in some scenarios to reduce closure time and suture material. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

SuturesSuture TechniquesBiomechanical PhenomenaFemaleHumansIn Vitro TechniquesMaleMaterials TestingTensile StrengthBarbed sutureKnotless closureLayered closureStrengthTensionTime

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.