Evidence map›Paper›PMID 40439752›Full record

ArticleFish physiology and biochemistry2025

Effects of progestogen neurosteroids on locomotor activity in zebrafish embryos and larvae.

Mandarin Mathouchanh, Charles A Lessman

Abstract read
In one paragraph

Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mandarin MathouchanhDepartment of Biological Sciences, The University of Memphis, Memphis, TN , 38152 , USA.
Charles A LessmanDepartment of Biological Sciences, The University of Memphis, Memphis, TN , 38152 , USA. clessman@memphis.edu.ORCID http://orcid.org/0000-0002-3033-5616

Funding

University of Memphis CAS Faculty Research GrantUniversity of Memphis Graduate Assistantship
6 · The paper itself

Abstract

The steroid hormone progesterone (P4) and related compounds called progestogens are well known for their effects on the reproductive system. However, their physiological roles outside reproduction are less understood. Additionally, there is limited information on the toxicological repercussions of environmental exposure to exogenous progestogens and how such exposure might impact the development and survival of animals living in contaminated habitats. Two progesterone-based neurosteroids, allopregnanolone and tetrahydrodeoxycorticosterone (THDOC), are known to enhance γ-aminobutyric acid type A (GABA

Indexed as

LocomotionNeurosteroidsProgestinsZebrafishAnimalsDesoxycorticosteroneEmbryo, NonmammalianLarvaPregnanoloneProgesteroneDesoxycorticosteroneNeurosteroidsPregnanoloneProgesteroneProgestinsBehaviorDeoxycorticosteroneGABAA receptorMembrane progesterone receptorNeuromuscular systemProgesterone

Identifiers

PMID40439752
PMCPMC12122642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.