Evidence map›Paper›PMID 40439721›Full record

ArticleAbdominal radiology (New York)2025

Improving prostate MRI quality and its diagnostic impact: a prospective quality improvement initiative.

Emily Knott, Jennifer Bullen, Rachel Harris, Kevin McDermott, Andrei Purysko, Ryan Ward

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Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily KnottCase Western Reserve University, Cleveland, USA.
Jennifer BullenCleveland Clinic, Cleveland, USA.
Rachel HarrisCleveland Clinic, Cleveland, USA.
Kevin McDermottCleveland Clinic, Cleveland, USA.
Andrei PuryskoCleveland Clinic, Cleveland, USA.
Ryan WardCleveland Clinic, Cleveland, USA. wardr3@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHigh-quality imaging is critical for accurate prostate cancer assessment using MRI. This study describes a quality improvement (QI) initiative for prostate MRI and evaluates the impact of image quality on diagnostic performance.

methodsIn this prospective study, 1328 patients underwent prostate MRI between March 2023 and March 2024. The QI initiative focused on patient preparation, protocol standardization, technologist education, and quality control. Image quality was prospectively scored using the Prostate Imaging Quality (PI-QUAL) system. Diagnostic performance was assessed by comparing the positive predictive value (PPV) of PI-RADS ≥ 3 lesions before and after the intervention and between exams with optimal (PI-QUAL ≥ 4) and suboptimal quality. Fisher's exact test was used for comparisons. Clinically significant prostate cancer (csPCa) was defined as Gleason Grade Group ≥ 2.

resultsThe proportion of PI-QUAL ≥ 4 exams increased from 67 to 84% after the intervention (p < 0.001). The PPV for any prostate cancer improved from 65 to 78% (p = 0.03), though the increase for csPCa (from 42 to 46%) was not statistically significant (p = 0.5). No significant difference in PPV was observed between optimal and suboptimal exams for any cancer (76% vs. 77%, p = 0.9) or csPCa (45% vs. 48%, p = 0.7).

conclusionThe QI initiative significantly improved image quality and overall cancer detection rates. However, the association between image quality and csPCa detection was not statistically significant, possibly due to greater improvements in T2-weighted images vs. diffusion weighted images and high reader expertise.

Indexed as

Magnetic Resonance ImagingProstatic NeoplasmsQuality ImprovementAgedHumansMaleMiddle AgedNeoplasm GradingProspective StudiesProstateMultiparametric MRIProstate cancerProstate imaging quality (PI-QUAL)Prostate imaging reporting and data systems (PI-RADS)Quality improvement

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.