Evidence map›Paper›PMID 40439696›Full record

ArticleMicrobiology (Reading, England)2025

Roles of human colonic bacteria in pectin utilization and associated cross-feeding networks revealed using synthetic co-cultures.

Michael Solvang, Freda M Farquharson, Graham Horgan, Sushila Pisano, Jesper Holck, Birgitte Zeuner, Wendy R Russell, Petra Louis

Abstract read
In one paragraph

Article in Microbiology (Reading, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. The Role ofInternational journal of molecular sciences · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael SolvangRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Freda M FarquharsonRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Graham HorganBiomathematics and Statistics Scotland, Aberdeen, UK.
Sushila PisanoRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Jesper HolckDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 2800 Kgs. Lyngby, Denmark.
Birgitte ZeunerDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 2800 Kgs. Lyngby, Denmark.
Wendy R RussellRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.
Petra LouisRowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary fibre is a crucial component of healthy diets via its action on the human gut microbiota, but fibre intake is well below current international dietary guidelines at the population level. Pectin is a fibre constituent in fruit and vegetables that has the promise to promote a healthy and diverse microbiota. It is a highly complex molecule, and its composition differs between plants. Here, we assessed the ability of a panel of 23 human gut bacteria to ferment pectins extracted from different plants based on their genome carriage of carbohydrate-active enzymes (CAZymes) and their growth in pure culture on several mono-, oligo- and polysaccharides, as well as pectins from different plant sources. Growth behaviour was overall in good agreement with CAZyme carriage, and the results were used to design synthetic co-culture communities with different combinations of pectin degraders, pectin cross-feeders and background strains not expected to play a major role in pectin degradation. For pectin degraders,

Indexed as

BacteriaColonGastrointestinal MicrobiomePectinsCoculture TechniquesDietary FiberFermentationHumansDietary FiberPectinscarbohydrate metabolismcross-feedingdietary fibrehuman gut microbiotapectinsynthetic co-culture

Identifiers

PMID40439696
PMCPMC12163728

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.