Evidence map›Paper›PMID 40439666›Full record

ArticleAge and ageing2025

The association between STOPPFall medication use and falls and fractures in community-dwelling older people.

Kate Doyle, Siobhan Scarlett, Silvin P Knight, Frank Moriarty, Amanda Lavan, Rose-Anne Kenny, Robert Briggs

Abstract read
In one paragraph

Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. [Falls and polypharmacy-an exploration of both the frequency and approaches to prevention].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Article
  2. Falls in older patients treated for cancer in French outpatient departments: screening and prevention-a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kate DoyleThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0002-2083-6281
Siobhan ScarlettThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.
Silvin P KnightThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.
Frank MoriartySchool of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.ORCID 0000-0001-9838-3625
Amanda LavanThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.
Rose-Anne KennyThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.
Robert BriggsThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0001-9585-2692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFalls and fractures are common among older people. The Screening Tool of Older Persons Prescriptions in older adults with high fall risk (STOPPFall) provides a comprehensive list of fall-risk-increasing drugs (FRIDs). This study assesses the association between STOPPFall medications and future falls/fractures among a large cohort of community-dwelling people ≥65 years using The Irish Longitudinal Study on Ageing (TILDA) Waves 1-6, collected from 2009 to 2021.

methodsSTOPPFall medications were recorded at Wave 1 and Wave 3. Falls/fractures were self-reported. Logistic regression models reporting odds ratios (ORs) assessed the association between STOPPFall medications and falls (including injurious/unexplained falls) and fractures at follow-up, adjusted for relevant covariates.

resultsOver one in four participants (777/2898, 27%) were prescribed one STOPPFall medication, and 15% (421/2898) were prescribed ≥2 STOPPFall medications. Over half of participants fell during follow-up, with 1/5 sustaining any fracture. Prescription of ≥2 STOPPFall medications was independently associated with all falls [OR 1.67 (95%CI 1.28-2.18); P < 0.001], injurious falls [OR 1.53 (95%CI 1.19-1.97); P = 0.001], unexplained falls [OR 1.86 (95%CI 1.43-2.42); P < 0.001], all fractures [OR 1.59 (95%CI 1.20-2.12); P = 0.001] and hip fractures [OR 1.75 (95%CI 1.00-3.05); P = 0.048]. Increasing prescription of ≥2 STOPPFall medications at Wave 3 was associated with increased likelihood of all falls and injurious falls.

conclusionPrescription of ≥2 STOPPFall medications is independently associated with an increased likelihood of all falls and all fractures. This is a potentially modifiable risk factor for falls, and an increased falls risk should be considered when prescribing these medications.

Indexed as

Accidental FallsFractures, BoneIndependent LivingAgedAged, 80 and overFemaleHumansIrelandLongitudinal StudiesMalePolypharmacyRisk AssessmentRisk Factorsdeprescribingfall-risk-increasing drugship fractureolder peopleunexplained falls

Identifiers

PMID40439666
PMCPMC12120935

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.