Evidence map›Paper›PMID 40439554›Full record

ArticleeLife2025

A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics.

Gabriele Baniulyte, Joseph T Wade

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gabriele BaniulyteDepartment of Biomedical Sciences, School of Public Health, University at Albany, SUNY, Rensselaer, United States.ORCID https://orcid.org/0000-0003-0235-7938
Joseph T WadeDepartment of Biomedical Sciences, School of Public Health, University at Albany, SUNY, Rensselaer, United States.ORCID https://orcid.org/0000-0002-9779-3160

Funding

Unexpected complexity in bacterial genomesR35GM144328 · NIGMS · WADSWORTH CENTER · PI Joseph Thomas Wade · 2022 to 2026
$2.6M
Pervasive transcription in bacterial genomesDP2OD007188 · OD · WADSWORTH CENTER · PI WADE, JOSEPH THOMAS · 2010 to 2010
$2.4M
NIGMS NIH HHS 1R35GM144328NIGMS NIH HHS R35 GM144328NIH HHS 1DP2OD007188NIH HHS DP2 OD007188
6 · The paper itself

Abstract

Expression of many bacterial genes is regulated by

Indexed as

Anti-Bacterial AgentsEscherichia coliGene Expression Regulation, BacterialOpen Reading FramesRibosomesEscherichia coli ProteinsProtein BiosynthesisToxin-Antitoxin SystemsAnti-Bacterial AgentsEscherichia coli ProteinsE. coliinfectious diseasemicrobiologyRho-dependent transcription terminationribosometranslationuORF

Identifiers

PMID40439554
PMCPMC12121999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.