Evidence map›Paper›PMID 40439532›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Management and Outcomes of Postoperative Airway Obstruction in Patients After Tissue-Augmentation Palatoplasty.

Pooja D Reddy, Soukaina Eljamri, Amber D Shaffer, Matthew Ford, Rachel Whelan, Allison Tobey, Noel Jabbour

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Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Pooja D ReddyUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0009-0004-0782-2602
Soukaina EljamriUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Amber D ShafferUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Matthew FordUPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Rachel WhelanUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Allison TobeyUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Noel JabbourUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize postoperative airway obstruction and evaluate management strategies in pediatric patients with cleft palate following tissue-augmentation palatoplasty (TAP). STUDY

designRetrospective case series.

settingSingle academic center.

methodsPatients with obstruction within 1 year of primary TAP between 2017 and 2023 were identified. Fisher's exact, Wilcoxon rank-sum, and Spearman rank correlation were used to investigate the relationship between TAP type, obstruction severity, interventions, and polysomnography (PSG) findings (Obstructive Apnea-Hypopnea Index [OAHI], total Apnea-Hypopnea Index [AHI]) and disposition details.

resultsOf the 129 patients who underwent primary TAP, 25 patients developed obstructive symptoms (19.4%); 52% female, 32% syndromic. In total, 17 underwent surgical intervention for obstruction (68.0%): revision palatoplasty/flap revision (8/25, 35%), tonsillectomy and partial cephalic adenoidectomy (10/25, 40%), and partial cephalic adenoidectomy only (5/25, 20%). In total, 11 were medically managed and 3 were observed without intervention. In nine patients with paired PSGs, there was no difference in pre-TAP and post-TAP AHI or OAHI. Patients who underwent surgical revision had worse pre-TAP AHI compared to those who did not undergo surgical revision (mean ± SD: 15.7 ± 5.9 vs 6.2 ± 4.1, P = .01).

conclusionTAP is a newer surgical technique used to address tissue deficiency in cleft palate repair. Most patients who experienced postoperative obstruction following TAP ultimately required surgical intervention, though preoperative AHI may help identify those at higher risk for obstruction. Future studies are necessary to evaluate the efficacy of earlier interventions and elucidate factors impacting obstruction risk and symptom resolution.

Indexed as

Airway ObstructionCleft PalatePlastic Surgery ProceduresPostoperative ComplicationsChildChild, PreschoolFemaleHumansInfantMalePolysomnographyReoperationRetrospective StudiesTreatment Outcomeairway obstructioncleft palatepediatricspolysomnographytissue‐augmentation palatoplasty

Identifiers

PMID40439532
PMCPMC12461788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.